Lipid droplet biogenesis and functions in health and disease
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
Lipid droplet biogenesis
TC Walther, J Chung… - Annual review of cell and …, 2017 - annualreviews.org
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …
Biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites
Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all
eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and …
eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and …
A conserved family of proteins facilitates nascent lipid droplet budding from the ER
V Choudhary, N Ojha, A Golden, WA Prinz - Journal of Cell Biology, 2015 - rupress.org
Lipid droplets (LDs) are found in all cells and play critical roles in lipid metabolism. De novo
LD biogenesis occurs in the endoplasmic reticulum (ER) but is not well understood. We …
LD biogenesis occurs in the endoplasmic reticulum (ER) but is not well understood. We …
Lipid droplet-organelle contact sites as hubs for fatty acid metabolism, trafficking, and metabolic channeling
Cells prepare for fluctuations in nutrient availability by storing energy in the form of neutral
lipids in organelles called Lipid Droplets (LDs). Upon starvation, fatty acids (FAs) released …
lipids in organelles called Lipid Droplets (LDs). Upon starvation, fatty acids (FAs) released …
Lipid droplets, lipophagy, and beyond
CW Wang - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2016 - Elsevier
Lipids are essential components for life. Their various structural and physical properties
influence diverse cellular processes and, thereby, human health. Lipids are not genetically …
influence diverse cellular processes and, thereby, human health. Lipids are not genetically …
Lipid Droplets and Peroxisomes: Key Players in Cellular Lipid Homeostasis or A Matter of Fat—Store 'em Up or Burn 'em Down
SD Kohlwein, M Veenhuis, IJ van der Klei - Genetics, 2013 - academic.oup.com
Lipid droplets (LDs) and peroxisomes are central players in cellular lipid homeostasis: some
of their main functions are to control the metabolic flux and availability of fatty acids (LDs and …
of their main functions are to control the metabolic flux and availability of fatty acids (LDs and …
The life cycle of lipid droplets
HF Hashemi, JM Goodman - Current opinion in cell biology, 2015 - Elsevier
Proteomic studies have revealed many potential functions of cytoplasmic lipid droplets, and
recent activity has confirmed that these bona fide organelles are central not only for lipid …
recent activity has confirmed that these bona fide organelles are central not only for lipid …
[HTML][HTML] Seipin and Nem1 establish discrete ER subdomains to initiate yeast lipid droplet biogenesis
Lipid droplets (LDs) are fat storage organelles that originate from the endoplasmic reticulum
(ER). Relatively little is known about how sites of LD formation are selected and which …
(ER). Relatively little is known about how sites of LD formation are selected and which …
Lipid droplets in cancer: from composition and role to imaging and therapeutics
P Antunes, A Cruz, J Barbosa, VDB Bonifácio, SN Pinto - Molecules, 2022 - mdpi.com
Cancer is the second most common cause of death worldwide, having its origin in the
abnormal growth of cells. Available chemotherapeutics still present major drawbacks …
abnormal growth of cells. Available chemotherapeutics still present major drawbacks …