Snake venomics: fundamentals, recent updates, and a look to the next decade

CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …

[PDF][PDF] Innovative approaches to neutralizing cobra venom: Advances in antivenomics and recombinant antivenoms

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
The King Cobra (Ophiophagus hannah) holds cultural significance and is one of the most
medically important venomous snakes worldwide. Envenomation by King Cobras often …

[HTML][HTML] Addressing the global snakebite crisis with geo-spatial analyses–Recent advances and future direction

AFV Pintor, N Ray, J Longbottom, CA Bravo-Vega… - Toxicon: X, 2021 - Elsevier
Venomous snakebite is a neglected tropical disease that annually leads to hundreds of
thousands of deaths or long-term physical and mental ailments across the developing world …

Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah)

CH Tan, KY Tan, SY Fung, NH Tan - BMC genomics, 2015 - Springer
Abstract Background The king cobra (Ophiophagus hannah) is widely distributed throughout
many parts of Asia. This study aims to investigate the complexity of Malaysian Ophiophagus …

Adaptive evolution of distinct prey-specific toxin genes in rear-fanged snake venom

CM Modahl, Mrinalini, S Frietze… - Proceedings of the …, 2018 - royalsocietypublishing.org
Venom proteins evolve rapidly, and as a trophic adaptation are excellent models for
predator–prey evolutionary studies. The key to a deeper understanding of venom evolution …

Functional proteomic analyses of Bothrops atrox venom reveals phenotypes associated with habitat variation in the Amazon

LF Sousa, JA Portes-Junior, CA Nicolau… - Journal of …, 2017 - Elsevier
Venom variability is commonly reported for venomous snakes including Bothrops atrox.
Here, we compared the composition of venoms from B. atrox snakes collected at Amazonian …

How the cobra got its flesh-eating venom: Cytotoxicity as a defensive innovation and its co-evolution with hooding, aposematic marking, and spitting

N Panagides, TNW Jackson, MP Ikonomopoulou… - Toxins, 2017 - mdpi.com
The cytotoxicity of the venom of 25 species of Old World elapid snake was tested and
compared with the morphological and behavioural adaptations of hooding and spitting. We …

Mapping proteoforms and protein complexes from king cobra venom using both denaturing and native top-down proteomics

RD Melani, OS Skinner, L Fornelli, GB Domont… - Molecular & Cellular …, 2016 - ASBMB
Characterizing whole proteins by top-down proteomics avoids a step of inference
encountered in the dominant bottom-up methodology when peptides are assembled …

Are ticks venomous animals?

A Cabezas-Cruz, JJ Valdés - Frontiers in zoology, 2014 - Springer
Introduction As an ecological adaptation venoms have evolved independently in several
species of Metazoa. As haematophagous arthropods ticks are mainly considered as …

Hydrogen peroxide from l-amino acid oxidase of king cobra (Ophiophagus hannah) venom attenuates Pseudomonas biofilms

U Singkham-In, W Thaveekarn, J Noiphrom, O Khow… - Scientific Reports, 2023 - nature.com
Because of the high incidence of Pseudomonas aeruginosa biofilms-related nosocomial
infections, venoms from common Thai snakes were tested. Although venoms from king …