Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products

M Ibrahim, E Ramadan, NE Elsadek, SE Emam… - Journal of Controlled …, 2022 - Elsevier
Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods
and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to …

Treatment-induced and pre-existing anti-PEG antibodies: prevalence, clinical implications, and future perspectives

SA Gaballa, T Shimizu, H Ando, H Takata… - Journal of …, 2023 - Elsevier
Polyethylene glycol (PEG) is a versatile polymer that is used in numerous pharmaceutical
applications like the food industry, a wide range of disinfectants, cosmetics, and many …

Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route

H Takata, T Shimizu, R Yamade, NE Elsadek… - Journal of Controlled …, 2023 - Elsevier
Modifying the surface of nanoparticles with polyethylene glycol (PEG) is a commonly used
approach for improving the in vitro stability of nanoparticles such as liposomes and …

Impact of Anti-PEG IgM Induced via the Topical Application of a Cosmetic Product Containing PEG Derivatives on the Antitumor Effects of PEGylated Liposomal …

SA Gaballa, T Shimizu, H Takata, H Ando… - Molecular …, 2024 - ACS Publications
Poly (ethylene glycol)(PEG) is used in many common products, such as cosmetics. PEG,
however, is also used to covalently conjugate drug molecules, proteins, or nanocarriers …

Accumulation of liposomes in metastatic tumor sites is not necessary for anti-cancer drug efficacy

J Kalra, J Baker, XX Sun, A Kyle, A Minchinton… - Journal of Translational …, 2024 - Springer
Background The tumor microenvironment is profoundly heterogeneous particularly when
comparing sites of metastases. Establishing the extent of this heterogeneity may provide …

Pharmacology of a Plant Virus Immunotherapy Candidate for Peritoneal Metastatic Ovarian Cancer

AO Omole, JF Affonso de Oliveira… - ACS Pharmacology & …, 2024 - ACS Publications
Due to the increasing incidence of cancer, there is a need to develop new platforms that can
combat this disease. Cancer immunotherapy is a platform that takes advantage of the …

Polyethylene glycol: Properties, applications, and challenges

SA Gaballa, Y Naguib, FM Mady… - Journal of advanced …, 2023 - jabps.journals.ekb.eg
Polyethylene glycol (PEG) is a versatile polymer with overwhelming properties that enhance
its abundant use in different applications. It is widely used in the food industry, various …