Hepatitis E virus infection

N Kamar, J Izopet, N Pavio, R Aggarwal… - Nature Reviews …, 2017 - nature.com
Hepatitis E virus (HEV) infection can lead to acute and chronic hepatitis as well as to
extrahepatic manifestations such as neurological and renal disease; it is the most common …

Hepatitis E virus

SU Emerson, RH Purcell - Reviews in medical virology, 2003 - Wiley Online Library
Hepatitis E virus (HEV) is a positive‐stranded RNA virus with a 7.2 kb genome that is
capped and polyadenylated. The virus is currently unclassified: the organisation of the …

[HTML][HTML] Zoonotic hepatitis E: animal reservoirs and emerging risks

N Pavio, XJ Meng, C Renou - Veterinary research, 2010 - ncbi.nlm.nih.gov
Hepatitis E virus (HEV) is responsible for enterically-transmitted acute hepatitis in humans
with two distinct epidemiological patterns. In endemic regions, large waterborne epidemics …

Hepatitis E Virus (HEV) strains in serum samples can replicate efficiently in cultured cells despite the coexistence of HEV antibodies: characterization of HEV virions in …

M Takahashi, T Tanaka, H Takahashi… - Journal of clinical …, 2010 - Am Soc Microbiol
We recently developed a cell culture system for hepatitis E virus (HEV) in PLC/PRF/5 and
A549 cells, using fecal specimens from HEV-infected patients. Since transfusion-associated …

Genetic variability and evolution of hepatitis E virus

H Okamoto - Virus research, 2007 - Elsevier
Hepatitis E virus (HEV) is the sole member of the genus Hepevirus in the family Hepeviridae.
HEV is transmitted primarily by the fecal–oral route, and water-borne epidemics are …

A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virus

J Graff, U Torian, H Nguyen, SU Emerson - Journal of virology, 2006 - Am Soc Microbiol
Hepatitis E virus replicons containing the neomycin resistance gene expressed from open
reading frames (ORFs) 2 and 3 were transfected into Huh-7 cells, and stable cell lines …

Hepatitis E virus genome structure and replication strategy

SP Kenney, XJ Meng - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
Hepatitis E virus (HEV) possesses many of the features of other positive-stranded RNA
viruses but also adds HEV-specific nuances, making its virus–host interactions unique. Slow …

ORF3 protein of hepatitis E virus is essential for virion release from infected cells

K Yamada, M Takahashi, Y Hoshino… - Journal of General …, 2009 - microbiologyresearch.org
The function of the hepatitis E virus (HEV) open reading frame 3 (ORF3) protein remains
unclear. To elucidate the role of the ORF3 protein in the virus life cycle, an infectious cDNA …

Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV

FF Huang, ZF Sun, SU Emerson… - Journal of general …, 2004 - microbiologyresearch.org
Avian hepatitis E virus (avian HEV), recently identified from a chicken with hepatitis–
splenomegaly syndrome in the United States, is genetically and antigenically related to …

Hepatitis E virus

SK Panda, D Thakral, S Rehman - Reviews in medical virology, 2007 - Wiley Online Library
Hepatitis E virus (HEV) is the aetiological agent of non‐HAV enterically transmitted hepatitis.
It is the major cause of sporadic as well as epidemic hepatitis, which is no longer confined to …