Mosquitoes are best known for transmitting human and animal viruses. However, they also
harbour mosquito-specific viruses (MSVs) as part of their microbiota. These are a group of …

Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa,
Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the …

Zoonotic viruses circulate in the natural reservoir and sporadically spill over into human
populations, resulting in endemics or pandemics. We previously found that the Chaoyang …

Zika virus (ZIKV) is an important re-emerging flavivirus that presents a significant threat to
human health worldwide. Despite its importance, no vaccines are approved for use in …

Binjari virus (BinJV) is a lineage II or dual-host affiliated insect-specific flavivirus previously
demonstrated as replication-deficient in vertebrate cells. Previous studies have shown that …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and the resulting
Coronavirus disease 2019 emerged in late 2019 and is responsible for significant morbidity …

West Nile virus (WNV), an arthropod-borne flavivirus, can cause severe symptoms, including
encephalitis, and death, posing a threat to public health and the economy. However, there is …

Chagas disease is an infectious disease of human and animal health concern, with 6–8
million chronic human infections and over 50,000 deaths throughout the Americas annually …

Vaccination is critical for the control and prevention of viral outbreaks, yet conventional
vaccine platforms may involve trade-offs between immunogenicity and safety. Insect-specific …

Flaviviruses subvert the host RNA decay machinery to produce subgenomic flavivirus RNA
(sfRNA), products of the 5'-3'exoribonuclease XRN1/Pacman stalling on secondary RNA …