Control of satellite cell function in muscle regeneration and its disruption in ageing
P Sousa-Victor, L García-Prat… - … Reviews Molecular Cell …, 2022 - nature.com
Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …
Sarcopenia: aging-related loss of muscle mass and function
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …
diminishes quality of life, and can lead to fall-related injuries, which require costly …
Tissue stem cells: architects of their niches
E Fuchs, HM Blau - Cell stem cell, 2020 - cell.com
Stem cells (SCs) maintain tissue homeostasis and repair wounds. Despite marked variation
in tissue architecture and regenerative demands, SCs often follow similar paradigms in …
in tissue architecture and regenerative demands, SCs often follow similar paradigms in …
Neutrophils in tissue injury and repair
J Wang - Cell and tissue research, 2018 - Springer
As one of the first defenders of innate immune response, neutrophils make a rapid and
robust response against infection or harmful agents. While traditionally regarded as suicidal …
robust response against infection or harmful agents. While traditionally regarded as suicidal …
Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines
J Bilski, P Pierzchalski, M Szczepanik, J Bonior… - Cells, 2022 - mdpi.com
Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …
NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are
susceptible to senescence during aging. We demonstrate the importance of the amount of …
susceptible to senescence during aging. We demonstrate the importance of the amount of …
Regulation of muscle growth and regeneration by the immune system
JG Tidball - Nature Reviews Immunology, 2017 - nature.com
Diseases of muscle that are caused by pathological interactions between muscle and the
immune system are devastating, but rare. However, muscle injuries that involve trauma and …
immune system are devastating, but rare. However, muscle injuries that involve trauma and …
Autophagy maintains stemness by preventing senescence
L García-Prat, M Martínez-Vicente, E Perdiguero… - Nature, 2016 - nature.com
During ageing, muscle stem-cell regenerative function declines. At advanced geriatric age,
this decline is maximal owing to transition from a normal quiescence into an irreversible …
this decline is maximal owing to transition from a normal quiescence into an irreversible …
Cell sources for cultivated meat: applications and considerations throughout the production workflow
J Reiss, S Robertson, M Suzuki - International Journal of Molecular …, 2021 - mdpi.com
Cellular agriculture is an emerging scientific discipline that leverages the existing principles
behind stem cell biology, tissue engineering, and animal sciences to create agricultural …
behind stem cell biology, tissue engineering, and animal sciences to create agricultural …
Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting
L Zanders, M Kny, A Hahn, S Schmidt… - Journal of cachexia …, 2022 - Wiley Online Library
Background Sepsis and inflammation can cause intensive care unit‐acquired weakness
(ICUAW). Increased interleukin‐6 (IL‐6) plasma levels are a risk factor for ICUAW. IL‐6 …
(ICUAW). Increased interleukin‐6 (IL‐6) plasma levels are a risk factor for ICUAW. IL‐6 …