Control of satellite cell function in muscle regeneration and its disruption in ageing

P Sousa-Victor, L García-Prat… - … Reviews Molecular Cell …, 2022 - nature.com
Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …

Sarcopenia: aging-related loss of muscle mass and function

L Larsson, H Degens, M Li, L Salviati… - Physiological …, 2018 - journals.physiology.org
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

Tissue stem cells: architects of their niches

E Fuchs, HM Blau - Cell stem cell, 2020 - cell.com
Stem cells (SCs) maintain tissue homeostasis and repair wounds. Despite marked variation
in tissue architecture and regenerative demands, SCs often follow similar paradigms in …

Neutrophils in tissue injury and repair

J Wang - Cell and tissue research, 2018 - Springer
As one of the first defenders of innate immune response, neutrophils make a rapid and
robust response against infection or harmful agents. While traditionally regarded as suicidal …

Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines

J Bilski, P Pierzchalski, M Szczepanik, J Bonior… - Cells, 2022 - mdpi.com
Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

H Zhang, D Ryu, Y Wu, K Gariani, X Wang, P Luan… - Science, 2016 - science.org
Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are
susceptible to senescence during aging. We demonstrate the importance of the amount of …

Regulation of muscle growth and regeneration by the immune system

JG Tidball - Nature Reviews Immunology, 2017 - nature.com
Diseases of muscle that are caused by pathological interactions between muscle and the
immune system are devastating, but rare. However, muscle injuries that involve trauma and …

Autophagy maintains stemness by preventing senescence

L García-Prat, M Martínez-Vicente, E Perdiguero… - Nature, 2016 - nature.com
During ageing, muscle stem-cell regenerative function declines. At advanced geriatric age,
this decline is maximal owing to transition from a normal quiescence into an irreversible …

Cell sources for cultivated meat: applications and considerations throughout the production workflow

J Reiss, S Robertson, M Suzuki - International Journal of Molecular …, 2021 - mdpi.com
Cellular agriculture is an emerging scientific discipline that leverages the existing principles
behind stem cell biology, tissue engineering, and animal sciences to create agricultural …

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting

L Zanders, M Kny, A Hahn, S Schmidt… - Journal of cachexia …, 2022 - Wiley Online Library
Background Sepsis and inflammation can cause intensive care unit‐acquired weakness
(ICUAW). Increased interleukin‐6 (IL‐6) plasma levels are a risk factor for ICUAW. IL‐6 …