Copper complexes of pyridine derivatives with superoxide scavenging and antimicrobial activities

T Suksrichavalit, S Prachayasittikul… - European journal of …, 2009 - Elsevier
Superoxide anions are reactive oxygen species that can attack biomolecules such as DNA,
lipids and proteins to cause many serious diseases. This study reports the synthesis of …

Gastrointestinal toxicity, antiinflammatory activity, and superoxide dismutase activity of copper and zinc complexes of the antiinflammatory drug indomethacin

CT Dillon, TW Hambley, BJ Kennedy… - Chemical Research …, 2003 - ACS Publications
Gastrointestinal (GI) toxicity is one of the major problems associated with antiinflammatory
drugs. The complexation of the powerful antiinflammatory drug (IndoH) by metal ions, as a …

[HTML][HTML] Copper complexes of nicotinic-aromatic carboxylic acids as superoxide dismutase mimetics

T Suksrichavalit, S Prachayasittikul, T Piacham… - Molecules, 2008 - mdpi.com
Nicotinic acid (also known as vitamin B3) is a dietary element essential for physiological and
antihyperlipidemic functions. This study reports the synthesis of novel mixed ligand …

[PDF][PDF] Helicobacter pylori, zinc and iron in oxidative stress-induced injury of gastric mucosa

J Dovhanj, K Kljaic, K Dodig-Curkovic… - Mini Reviews in …, 2009 - academia.edu
A number of study have suggested a relationship between Helicobacter pylori infection and
oxidative stress in the gastric epithelium. The oxidant-induced changes in zinc, iron, and …

Protective effect of copper II‐albumin complex against aflatoxin B1‐induced hepatocellular toxicity: The impact of Nrf2, PPAR‐γ, and NF‐kB in these protective effects

HM Abo‐Hiemad, AY Nassar, AR Shatat… - Journal of Food …, 2022 - Wiley Online Library
Abstract Copper II‐Albumin complex (Cu‐II‐Albumin complex) is a novel therapeutic target
that has been used as anti‐inflammatory, antioxidant, and anti‐gastrointestinal toxicity. In …

A novel therapeutic drug (copper nicotinic acid complex) for non‐alcoholic fatty liver

RHM Salama, AYA Nassar, AAM Nafady… - Liver …, 2007 - Wiley Online Library
Background: Fatty liver is the accumulation of fat in liver cells, which leads to disruption of
the normal liver structure and function. Methods: A non‐alcoholic fatty liver rat model …

A pioneer study on the anti-ulcer activities of copper nicotinate complex [CuCl (HNA) 2] in experimental gastric ulcer induced by aspirin-pyloris ligation model (Shay …

MJFA Tuorkey, KK Abdul-Aziz - Biomedicine & pharmacotherapy, 2009 - Elsevier
This study was planned to look for a more rational mechanism (s) that could explain the anti-
ulcer activity of copper nicotinate complex, since the mechanism whereby it prevents …

Measurement of Trace Elements (Zinc, Copper, Magnesium, and Iron) in the Saliva of Horses: Validation Data and Changes in Equine Gastric Ulcer Syndrome (EGUS …

A Muñoz-Prieto, JJ Cerón, F Tecles, MM Cuervo… - Animals, 2024 - mdpi.com
The objective of this study was to evaluate the possible use of spectrophotometric assays for
the measurement of trace elements, including Zinc (Zn), Copper (Cu), Magnesium (Mg), and …

Solubility product and total solubility in water of copper (II) nicotinate

AV Levanov, FI Gadziyeva, IY Kaplin… - The Journal of Chemical …, 2024 - Elsevier
A method for determining the solubility product of sparingly soluble copper (II) salts based
on the data of precipitation potentiometric titration with a copper indicator electrode is …

Protective and antioxidant effects of copper-nicotinate complex against glycerol-induced nephrotoxicity in rats

A Medhat Hegazy, AS Hafez, RM Eid - Drug and Chemical …, 2020 - Taylor & Francis
Copper-nicotinate complex (CNC) has antioxidant activities through scavenging of free
radicals formed inside the body. CNC also has anti-tumor and anti-inflammatory activities …