Nanoparticle-based drug delivery systems to overcome gastric cancer drug resistance

K Nejati, M Rastegar, F Fathi, M Dadashpour… - Journal of Drug Delivery …, 2022 - Elsevier
Gastric cancer (GC) results from deregulated cell growth in the stomach. Despite significant
efforts and recent advancements in the treatment of gastric cancer, it remains a life …

A review of research progress in multidrug-resistance mechanisms in gastric cancer

T Ruan, W Liu, K Tao, C Wu - OncoTargets and therapy, 2020 - Taylor & Francis
Gastric cancer is one of the most common malignant tumors, and it is also one of the leading
causes of cancer death worldwide. Because of its insidious symptoms and lack of early …

Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

H Fu, C Wang, D Yang, Z Wei, J Xu… - Journal of cellular …, 2018 - Wiley Online Library
In this study, we aimed to investigate the effects of curcumin on cell activities of gastric
cancer (GC), and the connection between curcumin and P53, as well as, PI3K signaling …

Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer

MH Kang, H Choi, M Oshima, JH Cheong, S Kim… - Nature …, 2018 - nature.com
The principle factors underlying gastric cancer (GC) development and outcomes are not well
characterized resulting in a paucity of validated therapeutic targets. To identify potential …

[HTML][HTML] Prediction of TP53 mutations by p53 immunohistochemistry and their prognostic significance in gastric cancer

HJ Hwang, SK Nam, H Park, Y Park… - … of pathology and …, 2020 - synapse.koreamed.org
Background Recently, molecular classifications of gastric cancer (GC) have been proposed
that include TP53 mutations and their functional activity. We aimed to demonstrate the …

Unraveling the influence of LncRNA in gastric cancer pathogenesis: a comprehensive review focus on signaling pathways interplay

H Elimam, SS Abdel Mageed, A Hatawsh, R Moussa… - Medical Oncology, 2024 - Springer
Gastric cancers (GCs) are among the most common and fatal malignancies in the world.
Despite our increasing understanding of the molecular mechanisms underlying GC, further …

Long noncoding RNA VCAN‐AS1 contributes to the progression of gastric cancer via regulating p53 expression

L Feng, J Li, F Li, H Li, S Bei, X Zhang… - Journal of cellular …, 2020 - Wiley Online Library
Gastric cancer (GC) is one of the most frequent malignancies worldwide. Long noncoding
RNAs (lncRNAs) are found to be largely implicated in various cancers, including GC …

Molecular classifications in gastric cancer: A call for interdisciplinary collaboration

C Díaz del Arco, MJ Fernández Aceñero… - International Journal of …, 2024 - mdpi.com
Gastric cancer (GC) is a heterogeneous disease, often diagnosed at advanced stages, with
a 5-year survival rate of approximately 20%. Despite notable technological advancements in …

Gastric Damage and Cancer-Associated Biomarkers in Helicobacter pylori-Infected Children

S George, Y Lucero, JP Torres… - Frontiers in …, 2020 - frontiersin.org
Helicobacter pylori (H. pylori) is well-known to be involved in gastric carcinogenesis,
associated with deregulation of cell proliferation and epigenetic changes in cancer-related …

Histopathological, molecular, and genetic profile of hereditary diffuse gastric cancer: current knowledge and challenges for the future

RS van der Post, I Gullo, C Oliveira, LH Tang… - Stem Cells, Pre …, 2016 - Springer
Familial clustering is seen in 10% of gastric cancer cases and approximately 1–3% of gastric
cancer arises in the setting of hereditary diffuse gastric cancer (HDGC). In families with …