Epicardial adipose tissue in contemporary cardiology
G Iacobellis - Nature reviews cardiology, 2022 - nature.com
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …
Non-canonical WNT signalling in cardiovascular disease: mechanisms and therapeutic implications
I Akoumianakis, M Polkinghorne… - Nature Reviews …, 2022 - nature.com
WNT signalling comprises a diverse spectrum of receptor-mediated pathways activated by a
large family of WNT ligands and influencing fundamental biological processes. WNT …
large family of WNT ligands and influencing fundamental biological processes. WNT …
Extracellular vesicles from epicardial fat facilitate atrial fibrillation
O Shaihov-Teper, E Ram, N Ballan, RY Brzezinski… - Circulation, 2021 - Am Heart Assoc
Background: The role of epicardial fat (eFat)-derived extracellular vesicles (EVs) in the
pathogenesis of atrial fibrillation (AF) has never been studied. We tested the hypothesis that …
pathogenesis of atrial fibrillation (AF) has never been studied. We tested the hypothesis that …
Hypercoagulopathy and adipose tissue exacerbated inflammation may explain higher mortality in COVID-19 patients with obesity
G Pasquarelli-do-Nascimento… - Frontiers in …, 2020 - frontiersin.org
COVID-19, caused by SARS-CoV-2, is characterized by pneumonia, lymphopenia,
exhausted lymphocytes and a cytokine storm. Several reports from around the world have …
exhausted lymphocytes and a cytokine storm. Several reports from around the world have …
COVID-19 myocarditis and prospective heart failure burden
Introduction: COVID-19 is causing considerable morbidity and mortality worldwide. Serious
respiratory complications aside, the heart is also frequently involved. The mechanisms and …
respiratory complications aside, the heart is also frequently involved. The mechanisms and …
Systemic inflammation and COVID-19 mortality in patients with major noncommunicable diseases: chronic coronary syndromes, diabetes and obesity
COVID-19 is currently considered an inflammatory disease affecting the entire organism. In
severe forms, an augmented inflammatory response leads to the fulminant “cytokine storm” …
severe forms, an augmented inflammatory response leads to the fulminant “cytokine storm” …
Epicardial adipose tissue is associated with extent of pneumonia and adverse outcomes in patients with COVID-19
K Grodecki, A Lin, A Razipour, S Cadet, PA McElhinney… - Metabolism, 2021 - Elsevier
Aim We sought to examine the association of epicardial adipose tissue (EAT) quantified on
chest computed tomography (CT) with the extent of pneumonia and adverse outcomes in …
chest computed tomography (CT) with the extent of pneumonia and adverse outcomes in …
Commentary: COVID-19 and obesity pandemics converge into a syndemic requiring urgent and multidisciplinary action
MA Hill, JR Sowers, CS Mantzoros - Metabolism, 2021 - Elsevier
While substantial evidence points towards obesity and associated cardiometabolic disorders
being a major factor for poor outcomes in SARS-CoV2 infections (COVID-19), the complexity …
being a major factor for poor outcomes in SARS-CoV2 infections (COVID-19), the complexity …
Obesity, metabolic phenotypes and COVID-19
The pandemic resulting from the acute respiratory SARS-CoV-2 infection and the associated
COVID-19 syndrome is reaching its third year and has impacted all regions of the globe. At …
COVID-19 syndrome is reaching its third year and has impacted all regions of the globe. At …
Browning epicardial adipose tissue: friend or foe?
E Doukbi, A Soghomonian, C Sengenès, S Ahmed… - Cells, 2022 - mdpi.com
The epicardial adipose tissue (EAT) is the visceral fat depot of the heart which is highly
plastic and in direct contact with myocardium and coronary arteries. Because of its singular …
plastic and in direct contact with myocardium and coronary arteries. Because of its singular …