Modern genome-scale methods that identify new genes, such as proteogenomics and
ribosome profiling, have revealed, to the surprise of many, that overlap in genes, open …

Our ability to generate bacterial strains with unique and increasingly complex functions has
rapidly expanded in recent times. The capacity for DNA synthesis is increasing and costing …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has highlighted the need for
rapid and sensitive protein detection and quantification in simple and robust formats for …

INTRODUCTION Cells respond to their environment, make decisions, build structures, and
coordinate tasks. Underlying these processes are computational operations performed by …

Rapid advances in synthetic biology are driving the development of genetically engineered
microbes as therapeutic agents for a multitude of human diseases, including cancer. The …

Metabolic engineering of microorganisms to produce desirable products on an industrial
scale can result in unbalanced cellular metabolic networks that reduce productivity and …

Lignin is one of the most abundant renewable resources on earth and is readily produced as
a sidestream during biomass fractioning. So far, these large quantities of lignin have been …

The redundancy of the genetic code implies that most amino acids are encoded by multiple
synonymous codons. In all domains of life, a biased frequency of synonymous codons is …

Bacterial genomes encode the biosynthetic potential to produce hundreds of thousands of
complex molecules with diverse applications, from medicine to agriculture and materials …

Conventional biosensors rely on the diffusion‐dominated transport of the target analyte to
the sensor surface. Consequently, they require an incubation step that may take several …