Causes, consequences, and treatment of metabolically unhealthy fat distribution

N Stefan - The lancet Diabetes & endocrinology, 2020 - thelancet.com
An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

Cardiovascular risk and body-fat abnormalities in HIV-infected adults

S Grinspoon, A Carr - New England Journal of Medicine, 2005 - Mass Medical Soc
Metabolic complications such as dyslipidemia, insulin resistance, and altered fat distribution
(loss of subcutaneous fat and relatively increased central fat) are common in adults infected …

Pulmonary rehabilitation in chronic obstructive pulmonary disease

T Troosters, R Casaburi, R Gosselink… - American journal of …, 2005 - atsjournals.org
In patients with pulmonary disease, disease severity and prognosis are determined not only
by lung function impairment (1, 2). In patients with mild, moderate, or severe disease …

The role of ghrelin in GH secretion and GH disorders

R Nass, BD Gaylinn, MO Thorner - Molecular and cellular endocrinology, 2011 - Elsevier
In humans, growth hormone (GH) is secreted from the anterior pituitary in a pulsatile pattern.
The traditional view is that this secretory pattern is driven by two counter regulatory …

Lipodystrophy: pathophysiology and advances in treatment

CG Fiorenza, SH Chou, CS Mantzoros - Nature Reviews Endocrinology, 2011 - nature.com
Lipodystrophy is a medical condition characterized by complete or partial loss of adipose
tissue. Not infrequently, lipodystrophy occurs in combination with pathological accumulation …

Central fat excess in polycystic ovary syndrome: relation to low-grade inflammation and insulin resistance

JJ Puder, S Varga, M Kraenzlin… - The Journal of …, 2005 - academic.oup.com
Background: It is controversial whether the polycystic ovary syndrome (PCOS) per se
increases low-grade chronic inflammation and whether this relates to central fat excess. In …

Comparison of DXA and CT in the assessment of body composition in premenopausal women with obesity and anorexia nervosa

MA Bredella, RH Ghomi, BJ Thomas, M Torriani… - …, 2010 - Wiley Online Library
Accurate methods for assessing body composition in subjects with obesity and anorexia
nervosa (AN) are important for determination of metabolic and cardiovascular risk factors …

Clinical, biochemical and histological differences between HIV‐associated NAFLD and primary NAFLD: a case–control study

I Vodkin, MA Valasek, R Bettencourt… - Alimentary …, 2015 - Wiley Online Library
Background There are limited data regarding the clinical, biochemical and liver histological
characteristics of patients with HIV‐associated nonalcoholic fatty liver disease (NAFLD), and …

[HTML][HTML] Metabolic effects of a growth hormone–releasing factor in patients with HIV

J Falutz, S Allas, K Blot, D Potvin, D Kotler… - … England Journal of …, 2007 - Mass Medical Soc
Background Visceral adipose tissue accumulates during antiretroviral therapy in many
patients who are infected with the human immunodeficiency virus (HIV); this process is …