Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

Cardiovascular diseases are the leading cause of death globally and are associated with
increasing financial expenditure. With the availability of next-generation sequencing …

Background Invasive cervical cancer (ICC) is caused by high-risk human papillomavirus
types (HR-HPVs) and is usually preceded by a long phase of intraepithelial neoplasia (CIN) …

The human genome encodes hundreds of transfer RNA (tRNA) genes but their individual
contribution to the tRNA pool is not fully understood. Deep sequencing of tRNA transcripts …

Introduction Osteoarthritis (OA) is a common disease worldwide leading to significant
morbidity. The underlying disease process is multifactorial however there is increasing focus …

Major depressive disorder (MDD) is a complex and debilitating illness whose etiology
remains unclear. Small RNA molecules, such as micro RNAs (miRNAs) have been …

Non-coding RNA (ncRNA) molecules have fundamental roles in cells and many are also
stable in body fluids as extracellular RNAs. In this study, we used RNA sequencing (RNA …

As an essential part of central dogma, RNA delivers genetic and regulatory information and
reflects cellular states. Based on high-throughput sequencing technologies, cumulating data …

Antidepressants (ADs) are the most common treatment for major depressive disorder (MDD).
However, only∼ 30% of patients experience adequate response after a single AD trial, and …

Although variation in gut microbiome composition has been linked with colorectal cancer
(CRC), the factors that mediate the interactions between CRC tumors and the microbiome …