The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of social,
cognitive, and affective functions that are commonly disrupted in mental illness. In this …

A central goal in systems neuroscience is the parcellation of the cerebral cortex into discrete
neurobiological “atoms”. Resting-state functional magnetic resonance imaging (rs-fMRI) …

The brain is constituted of multiple networks of functionally correlated brain areas, out of
which the default-mode network (DMN) is the largest. Most existing research into the DMN …

Depression is associated with alterations in corticostriatal reward circuitry. One
pathophysiological pathway that may drive these changes is inflammation. Biomarkers of …

Resting state functional connectivity reveals intrinsic, spontaneous networks that elucidate
the functional architecture of the human brain. However, valid statistical analysis used to …

The basal ganglia, thalamus, and cerebral cortex form an interconnected network implicated
in many neurological and psychiatric illnesses. A better understanding of cortico-subcortical …

The cerebral cortex communicates with the cerebellum via polysynaptic circuits. Separate
regions of the cerebellum are connected to distinct cerebral areas, forming a complex …

Recent years have seen significant progress in our understanding of the neural substrates of
motor skill learning. Advances in neuroimaging provide new insight into functional …

Background Studies using positron emission tomography to image striatal dopamine
function, have demonstrated that individuals with schizophrenia display increases in …