As one of the most important cancer treatment strategies, conventional chemotherapy has
substantial side effects and leads easily to cancer treatment failure. Therefore, exploring and …

Flavonoids such as baohuoside I and icaritin are the major active compounds in Epimedii
Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly …

Over the years, click and bioorthogonal reactions have been the subject of considerable
research efforts. These high-performance chemical reactions have been developed to meet …

Nanotherapeutics exhibit unique advantages in clinical outcomes compared with
conventional small molecular drugs. The past three decades have seen intensive research …

Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

To promote the clinical theranostic performances of platinum‐based anticancer drugs,
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …

The impermeable barrier of solid tumors due to the complexity of their components limits the
treatment effect of nanomedicine and hinders its clinical translation. Several methods are …

Conspectus Nanomedicine holds significant potential to improve the efficacy of cancer
immunotherapy. Thus far, nanomedicines, ie, 1–100 (0) nm sized drug delivery systems …

Tumor hypoxia-responsive size-switchable nanosystems for precise delivery of drug into
deep tumor show great prospects for killing cancer cells with high specificity and minimal …