Nanotechnology-assisted metered-dose inhalers (MDIs) for high-performance pulmonary drug delivery applications
Purpose Respiratory disorders pose a major threat to the morbidity and mortality to public
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …
Functionalization of polymers for intracellular protein delivery
Y Zhang, J Shi, B Ma, YN Zhou, H Yong, J Li… - Progress in Polymer …, 2023 - Elsevier
With the growing demand for clinically reliable therapeutics, traditional small molecule drugs
are increasingly limited by their short circulation duration, low bioavailability, and poor …
are increasingly limited by their short circulation duration, low bioavailability, and poor …
Biodegradation of pharmaceutical compounds in industrial wastewater using biological treatment: a comprehensive overview
A Moghaddam, D Khayatan… - International Journal of …, 2023 - Springer
The indirect ingestion of pharmaceuticals in water has been proven to have adverse effects
on humans according to a number of studies. Pharmaceutical compounds (PhCs) are found …
on humans according to a number of studies. Pharmaceutical compounds (PhCs) are found …
The potential use of bacteria and bacterial derivatives as drug delivery systems for viral infection
A Faghihkhorasani, HH Ahmed, NM Mashool, M Alwan… - Virology Journal, 2023 - Springer
Viral infections in humans are responsible for fatalities worldwide and contribute to the
incidence of various human ailments. Controllable targeted medicine delivery against many …
incidence of various human ailments. Controllable targeted medicine delivery against many …
[HTML][HTML] Nebulised delivery of RNA formulations to the lungs: From aerosol to cytosol
MT Neary, LM Mulder, PS Kowalski… - Journal of Controlled …, 2024 - Elsevier
In the past decade RNA-based therapies such as small interfering RNA (siRNA) and
messenger RNA (mRNA) have emerged as new and ground-breaking therapeutic agents for …
messenger RNA (mRNA) have emerged as new and ground-breaking therapeutic agents for …
Liposomes or extracellular vesicles: a comprehensive comparison of both lipid bilayer vesicles for pulmonary drug delivery
The rapid and non-invasive pulmonary drug delivery (PDD) has attracted great attention
compared to the other routes. However, nanoparticle platforms, like liposomes (LPs) and …
compared to the other routes. However, nanoparticle platforms, like liposomes (LPs) and …
Janus kinase/signal transducers and activator of transcription (JAK/STAT) and its role in Lung inflammatory disease
A key signaling channel for the signal transduction of several crucial cytokines implicated in
sepsis is the JAK/STAT system. Once cytokines attach to the proper receptors, JAK kinases …
sepsis is the JAK/STAT system. Once cytokines attach to the proper receptors, JAK kinases …
Opportunities and challenges of RiPP-based therapeutics
IPM Pfeiffer, MP Schröder, S Mordhorst - Natural Product Reports, 2024 - pubs.rsc.org
Covering: up to 2024Ribosomally synthesised and post-translationally modified peptides
(RiPPs) comprise a substantial group of peptide natural products exhibiting noteworthy …
(RiPPs) comprise a substantial group of peptide natural products exhibiting noteworthy …
Future prospects of natural polymer-based drug delivery systems in combating lung diseases
S Yasamineh, O Gholizadeh, HG Kalajahi… - … materials based drug …, 2023 - Springer
Natural polymers have been widely studied as the carriers for the transfer of medications
and different therapeutic molecules, which have attracted significant attention. Natural …
and different therapeutic molecules, which have attracted significant attention. Natural …
Mannosylated polydopamine nanoparticles alleviate radiation-induced pulmonary fibrosis by targeting M2 macrophages and inhibiting the TGF-β1/Smad3 signaling …
L Shen, S Fu, Y Chen, W Li, S Liu, Z Li, J Li, Y Li… - Colloids and Surfaces B …, 2023 - Elsevier
Radiation-induced pulmonary fibrosis (RIPF), one type of pulmonary interstitial diseases, is
frequently observed following radiation therapy for chest cancer or accidental radiation …
frequently observed following radiation therapy for chest cancer or accidental radiation …