Nanotechnology-assisted metered-dose inhalers (MDIs) for high-performance pulmonary drug delivery applications

R Kumar, P Mehta, KR Shankar, MAK Rajora… - Pharmaceutical …, 2022 - Springer
Purpose Respiratory disorders pose a major threat to the morbidity and mortality to public
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …

Functionalization of polymers for intracellular protein delivery

Y Zhang, J Shi, B Ma, YN Zhou, H Yong, J Li… - Progress in Polymer …, 2023 - Elsevier
With the growing demand for clinically reliable therapeutics, traditional small molecule drugs
are increasingly limited by their short circulation duration, low bioavailability, and poor …

Biodegradation of pharmaceutical compounds in industrial wastewater using biological treatment: a comprehensive overview

A Moghaddam, D Khayatan… - International Journal of …, 2023 - Springer
The indirect ingestion of pharmaceuticals in water has been proven to have adverse effects
on humans according to a number of studies. Pharmaceutical compounds (PhCs) are found …

The potential use of bacteria and bacterial derivatives as drug delivery systems for viral infection

A Faghihkhorasani, HH Ahmed, NM Mashool, M Alwan… - Virology Journal, 2023 - Springer
Viral infections in humans are responsible for fatalities worldwide and contribute to the
incidence of various human ailments. Controllable targeted medicine delivery against many …

[HTML][HTML] Nebulised delivery of RNA formulations to the lungs: From aerosol to cytosol

MT Neary, LM Mulder, PS Kowalski… - Journal of Controlled …, 2024 - Elsevier
In the past decade RNA-based therapies such as small interfering RNA (siRNA) and
messenger RNA (mRNA) have emerged as new and ground-breaking therapeutic agents for …

Liposomes or extracellular vesicles: a comprehensive comparison of both lipid bilayer vesicles for pulmonary drug delivery

A Al-Jipouri, SH Almurisi, K Al-Japairai, LM Bakar… - Polymers, 2023 - mdpi.com
The rapid and non-invasive pulmonary drug delivery (PDD) has attracted great attention
compared to the other routes. However, nanoparticle platforms, like liposomes (LPs) and …

Janus kinase/signal transducers and activator of transcription (JAK/STAT) and its role in Lung inflammatory disease

M Purohit, G Gupta, O Afzal, ASA Altamimi… - Chemico-biological …, 2023 - Elsevier
A key signaling channel for the signal transduction of several crucial cytokines implicated in
sepsis is the JAK/STAT system. Once cytokines attach to the proper receptors, JAK kinases …

Opportunities and challenges of RiPP-based therapeutics

IPM Pfeiffer, MP Schröder, S Mordhorst - Natural Product Reports, 2024 - pubs.rsc.org
Covering: up to 2024Ribosomally synthesised and post-translationally modified peptides
(RiPPs) comprise a substantial group of peptide natural products exhibiting noteworthy …

Future prospects of natural polymer-based drug delivery systems in combating lung diseases

S Yasamineh, O Gholizadeh, HG Kalajahi… - … materials based drug …, 2023 - Springer
Natural polymers have been widely studied as the carriers for the transfer of medications
and different therapeutic molecules, which have attracted significant attention. Natural …

Mannosylated polydopamine nanoparticles alleviate radiation-induced pulmonary fibrosis by targeting M2 macrophages and inhibiting the TGF-β1/Smad3 signaling …

L Shen, S Fu, Y Chen, W Li, S Liu, Z Li, J Li, Y Li… - Colloids and Surfaces B …, 2023 - Elsevier
Radiation-induced pulmonary fibrosis (RIPF), one type of pulmonary interstitial diseases, is
frequently observed following radiation therapy for chest cancer or accidental radiation …