Biological and bioinspired thermal energy regulation and utilization

S An, B Shi, M Jiang, B Fu, C Song, P Tao… - Chemical …, 2023 - ACS Publications
The regulation and utilization of thermal energy is increasingly important in modern society
due to the growing demand for heating and cooling in applications ranging from buildings, to …

TRPV4: a physio and pathophysiologically significant ion channel

T Rosenbaum, M Benítez-Angeles… - International journal of …, 2020 - mdpi.com
Transient Receptor Potential (TRP) channels are a family of ion channels whose members
are distributed among all kinds of animals, from invertebrates to vertebrates. The importance …

Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel

KD Nadezhdin, A Neuberger, YA Trofimov… - Nature structural & …, 2021 - nature.com
Numerous physiological functions rely on distinguishing temperature through temperature-
sensitive transient receptor potential channels (thermo-TRPs). Although the function of …

Photothermoelectric Response of Ti3C2Tx MXene Confined Ion Channels

S Hong, G Zou, H Kim, D Huang, P Wang… - ACS …, 2020 - ACS Publications
With recent growing interest in biomimetic smart nanochannels, a biological sensory
transduction in response to external stimuli has been of particular interest in the …

Ligand-binding sites in vanilloid-subtype TRP channels

MV Yelshanskaya, AI Sobolevsky - Frontiers in Pharmacology, 2022 - frontiersin.org
Vanilloid-subfamily TRP channels TRPV1-6 play important roles in various physiological
processes and are implicated in numerous human diseases. Advances in structural biology …

Intracellular thermometry uncovers spontaneous thermogenesis and associated thermal signaling

K Okabe, S Uchiyama - Communications Biology, 2021 - nature.com
Conventional thermal biology has elucidated the physiological function of temperature
homeostasis through spontaneous thermogenesis and responses to variations in …

A cold-sensing receptor encoded by a glutamate receptor gene

J Gong, J Liu, EA Ronan, F He, W Cai, M Fatima… - Cell, 2019 - cell.com
In search of the molecular identities of cold-sensing receptors, we carried out an unbiased
genetic screen for cold-sensing mutants in C. elegans and isolated a mutant allele of glr-3 …

Unstructural biology of TRP ion channels: the role of intrinsically disordered regions in channel function and regulation

B Goretzki, C Guhl, F Tebbe, JM Harder… - Journal of Molecular …, 2021 - Elsevier
The first genuine high-resolution single particle cryo-electron microscopy structure of a
membrane protein determined was a transient receptor potential (TRP) ion channel, TRPV1 …

Sequence and structural conservation reveal fingerprint residues in TRP channels

D Cabezas-Bratesco, FA Mcgee, CK Colenso, K Zavala… - Elife, 2022 - elifesciences.org
Transient receptor potential (TRP) proteins are a large family of cation-selective channels,
surpassed in variety only by voltage-gated potassium channels. Detailed molecular …

Wandering between hot and cold: temperature dose-dependent responses

T Zhu, M van Zanten, I De Smet - Trends in Plant Science, 2022 - cell.com
Plants in most natural habitats are exposed to a continuously changing environment,
including fluctuating temperatures. Temperature variations can trigger acclimation or …