Aim To report seizure outcomes in children with GATOR1 gene complex disorders who
underwent epilepsy surgery and perform a systematic literature search to study the available …

Objective DEPDC5 emerges to play a vital role in focal epilepsy. However, genotype–
phenotype correlation in DEPDC5‐related focal epilepsies is challenging and controversial …

Hemimegalencephaly (HME) is a rare hamartomatous congenital malformation of the brain
characterized by dysplastic overgrowth of either one of the cerebral hemispheres. HME is …

Introduction Variants in GATOR1 genes are well established in focal epilepsy syndromes. A
strong association of GATOR1 variants with drug-resistant epilepsy as well as an increased …

Disheveled EGL-10 and pleckstrin domain-containing protein 5 (DEPDC5) is a key member
of the GAP activity toward rags complex 1 complex, which inhibits the mammalian target of …