Isoflavones: estrogenic activity, biological effect and bioavailability
DC Vitale, C Piazza, B Melilli, F Drago… - European journal of drug …, 2013 - Springer
Isoflavones are phytoestrogens with potent estrogenic activity; genistein, daidzein and
glycitein are the most active isoflavones found in soy beans. Phytoestrogens have similarity …
glycitein are the most active isoflavones found in soy beans. Phytoestrogens have similarity …
First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics
Glucuronidation mediated by UDP-glucuronosyltransferases (UGTs) is a significant
metabolic pathway that facilitates efficient elimination of numerous endobiotics and …
metabolic pathway that facilitates efficient elimination of numerous endobiotics and …
Bioaccessibility and bioavailability of phenolic compounds
Modern epidemiological and interventional studies have demonstrated that various
bioactivities including antioxidant, antiproliferative, immune-regulatory, hormonal-regulation …
bioactivities including antioxidant, antiproliferative, immune-regulatory, hormonal-regulation …
[图书][B] Handbook of nutraceuticals and functional foods
REC Wildman, R Wildman, TC Wallace - 2016 - taylorfrancis.com
Scientific advances in this field have not only given us a better understanding of what is an
optimal diet, but has allowed food and nutraceutical companies to market products with …
optimal diet, but has allowed food and nutraceutical companies to market products with …
A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
Z Guo, Y Lou, M Kong, Q Luo, Z Liu, J Wu - International journal of …, 2019 - mdpi.com
Astragali radix (AR) is one of the most widely used traditional Chinese herbal medicines.
Modern pharmacological studies and clinical practices indicate that AR possesses various …
Modern pharmacological studies and clinical practices indicate that AR possesses various …
Methylated flavonoids have greatly improved intestinal absorption and metabolic stability
X Wen, T Walle - Drug metabolism and disposition, 2006 - ASPET
To better understand the relationship between the chemical structure and biological fate of
dietary polyphenols, the hepatic metabolic stability and intestinal absorption of methylated …
dietary polyphenols, the hepatic metabolic stability and intestinal absorption of methylated …
Bioavailability challenges associated with development of anti-cancer phenolics
S Gao, M Hu - Mini reviews in medicinal chemistry, 2010 - ingentaconnect.com
Phenolics including many polyphenols and flavonoids have the potentials to become
chemoprevention and chemotherapy agents. However, poor bioavailability limits their …
chemoprevention and chemotherapy agents. However, poor bioavailability limits their …
Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME
Genistein, one of the most active natural flavonoids, exerts various biological effects
including chemoprevention, antioxidation, antiproliferation and anticancer. More than 30 …
including chemoprevention, antioxidation, antiproliferation and anticancer. More than 30 …
Bioavailability issues in studying the health effects of plant polyphenolic compounds
CS Yang, S Sang, JD Lambert… - Molecular nutrition & food …, 2008 - Wiley Online Library
Polyphenolic compounds are common in the diet and have been suggested to have a
number of beneficial health effects including prevention of cancer, cardiovascular disease …
number of beneficial health effects including prevention of cancer, cardiovascular disease …
Dietary flavonoids for immunoregulation and cancer: Food design for targeting disease
Flavonoids, one of the most abundant phytochemicals in a diet rich in fruits and vegetables,
have been recognized as possessing anti-proliferative, antioxidant, anti-inflammatory, and …
have been recognized as possessing anti-proliferative, antioxidant, anti-inflammatory, and …