Current scenario of quinolone hybrids with potential antibacterial activity against ESKAPE pathogens

J Gao, H Hou, F Gao - European Journal of Medicinal Chemistry, 2023 - Elsevier
Abstract The ESKAPE (Escherichia coli/E. coli, Staphylococcus aureus/S. aureus, Klebsiella
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …

Conjugation of antimicrobial peptides to enhance therapeutic efficacy

SP Selvaraj, JY Chen - European Journal of Medicinal Chemistry, 2023 - Elsevier
The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

Photocatalytic degradation of four emerging antibiotic contaminants and toxicity assessment in wastewater: A comprehensive study

M Sharma, D Rajput, V Kumar, I Jatain… - Environmental …, 2023 - Elsevier
Excessive usage and unrestricted discharge of antibiotics in the environment lead to their
accumulation in the ecosystem due to their highly stable and non-biodegradation nature …

Towards azeotropic MeOH-MTBE separation using pervaporation chitosan-based deep eutectic solvent membranes

R Castro-Muñoz, A Msahel, F Galiano… - Separation and …, 2022 - Elsevier
Deep eutectic solvents (DESs) are a new class of solvents that can offset some of the major
drawbacks of common solvents and ionic liquids. When dealing with the preparation of …

[HTML][HTML] Combinatorial wound dressings loaded with synergistic antibiotics in the treatment of chronic infected wounds

L Miranda-Calderon, C Yus, CR de Ganuza… - Chemical Engineering …, 2023 - Elsevier
Advanced medicated wound dressings fabricated by electrospinning and electrospraying
were prepared for the eradication of topical bacterial infections potentially applied in the …

The antibacterial activity of fluoroquinolone derivatives: An update (2018–2021)

Y Jia, L Zhao - European journal of medicinal chemistry, 2021 - Elsevier
Bacterial infection is amongst the most common diseases in community and hospital
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …

Peptides as pharmacological carriers to the brain: promises, shortcomings and challenges

S Parrasia, I Szabò, M Zoratti… - Molecular …, 2022 - ACS Publications
Central nervous system (CNS) diseases are among the most difficult to treat, mainly
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …

[HTML][HTML] Potential of cell-penetrating peptides (CPPs) in delivery of antiviral therapeutics and vaccines

I Sadeghian, R Heidari, S Sadeghian, MJ Raee… - European Journal of …, 2022 - Elsevier
Viral infections are a great threat to human health. Currently, there are no effective vaccines
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …

Cell-penetrating peptides (CPPs) as therapeutic and diagnostic agents for cancer

RA Bottens, T Yamada - Cancers, 2022 - mdpi.com
Simple Summary Crossing biological barriers is often required for drug delivery. Cell-
penetrating peptides (CPPs) are short strands of amino acids that have been widely used as …

Cell-penetrating peptides and transportan

Ü Langel - Pharmaceutics, 2021 - mdpi.com
In the most recent 25–30 years, multiple novel mechanisms and applications of cell-
penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery …