Decision-related activity in sensory neurons: correlations among neurons and with behavior

H Nienborg, M R. Cohen… - Annual review of …, 2012 - annualreviews.org
Neurons in early sensory cortex show weak but systematic correlations with perceptual
decisions when trained animals perform at psychophysical threshold. These correlations are …

Inference in the brain: statistics flowing in redundant population codes

X Pitkow, DE Angelaki - Neuron, 2017 - cell.com
It is widely believed that the brain performs approximate probabilistic inference to estimate
causal variables in the world from ambiguous sensory data. To understand these …

Neural correlates of multisensory cue integration in macaque MSTd

Y Gu, DE Angelaki, GC DeAngelis - Nature neuroscience, 2008 - nature.com
Human observers combine multiple sensory cues synergistically to achieve greater
perceptual sensitivity, but little is known about the underlying neuronal mechanisms. We …

Decision-related activity in sensory neurons reflects more than a neuron's causal effect

H Nienborg, BG Cumming - Nature, 2009 - nature.com
During perceptual decisions, the activity of sensory neurons correlates with a subject's
percept, even when the physical stimulus is identical,,,,,,,,. The origin of this correlation is …

Feedback determines the structure of correlated variability in primary visual cortex

AG Bondy, RM Haefner, BG Cumming - Nature neuroscience, 2018 - nature.com
The variable responses of sensory neurons tend to be weakly correlated (spike-count
correlation, r sc). This is widely thought to reflect noise in shared afferents, in which case r sc …

How can single sensory neurons predict behavior?

X Pitkow, S Liu, DE Angelaki, GC DeAngelis, A Pouget - Neuron, 2015 - cell.com
Single sensory neurons can be surprisingly predictive of behavior in discrimination tasks.
We propose this is possible because sensory information extracted from neural populations …

Inferring decoding strategies from choice probabilities in the presence of correlated variability

RM Haefner, S Gerwinn, JH Macke, M Bethge - Nature neuroscience, 2013 - nature.com
The activity of cortical neurons in sensory areas covaries with perceptual decisions, a
relationship that is often quantified by choice probabilities. Although choice probabilities …

Visual evidence accumulation guides decision-making in unrestrained mice

O Odoemene, S Pisupati, H Nguyen… - Journal of …, 2018 - Soc Neuroscience
The ability to manipulate neural activity with precision is an asset in uncovering neural
circuits for decision-making. Diverse tools for manipulating neurons are available for mice …

Feedforward and feedback sources of choice probability in neural population responses

BG Cumming, H Nienborg - Current opinion in neurobiology, 2016 - Elsevier
Highlights•Decision-related activity (choice-probabilities [CPs]) in sensory neurons is widely
found.•Correlated variability in sensory neurons limits information in some cases.•The …

Psychophysical reverse correlation reflects both sensory and decision-making processes

G Okazawa, L Sha, BA Purcell, R Kiani - Nature communications, 2018 - nature.com
Goal-directed behavior depends on both sensory mechanisms that gather information from
the outside world and decision-making mechanisms that select appropriate behavior based …