Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria

I Alav, J Kobylka, MS Kuth, KM Pos, M Picard… - Chemical …, 2021 - ACS Publications
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

Microcins in Enterobacteriaceae: Peptide Antimicrobials in the Eco-Active Intestinal Chemosphere

F Baquero, VF Lanza, MR Baquero… - Frontiers in …, 2019 - frontiersin.org
Microcins are low-molecular-weight, ribosomally produced, highly stable, bacterial-inhibitory
molecules involved in competitive, and amensalistic interactions between …

Learning the ABCs one at a time: structure and mechanism of ABC transporters

RC Ford, K Beis - Biochemical Society Transactions, 2019 - portlandpress.com
ATP-binding cassette (ABC) transporters are essential proteins that are found across all
kingdoms of life. ABC transporters harness the energy of ATP hydrolysis to drive the import …

Metagenomics reveal arbuscular mycorrhizal fungi altering functional gene expression of rhizosphere microbial community to enhance Iris tectorum's resistance to Cr …

W Zhao, Z Chen, X Yang, L Sheng, H Mao… - Science of The Total …, 2023 - Elsevier
Chromium (Cr) can disrupt a plant's normal physiological and metabolic functions and
severely impact the microenvironment. However, limited studies have investigated the …

FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

E Lerner, A Barth, J Hendrix, B Ambrose, V Birkedal… - Elife, 2021 - elifesciences.org
Single-molecule FRET (smFRET) has become a mainstream technique for studying
biomolecular structural dynamics. The rapid and wide adoption of smFRET experiments by …

A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds

S Rempel, C Gati, M Nijland, C Thangaratnarajah… - Nature, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent
of tuberculosis,–. Although Mtb can synthesize vitamin B12 (cobalamin) de novo, uptake of …

Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers

M de Boer, G Gouridis, R Vietrov, SL Begg… - Elife, 2019 - elifesciences.org
Substrate-binding proteins (SBPs) are associated with ATP-binding cassette importers and
switch from an open to a closed conformation upon substrate binding, providing specificity …

Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses

L Wang, ZL Johnson, MR Wasserman, J Levring… - Elife, 2020 - elifesciences.org
ATP-binding cassette (ABC) transporters are molecular pumps ubiquitous across all
kingdoms of life. While their structures have been widely reported, the kinetics governing …

[HTML][HTML] An integrated transport mechanism of the maltose ABC importer

R Mächtel, A Narducci, DA Griffith, T Cordes… - Research in …, 2019 - Elsevier
ATP-binding cassette (ABC) transporters use the energy of ATP hydrolysis to transport a
large diversity of molecules actively across biological membranes. A combination of …

The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide

F Baquero, K Beis, DJ Craik, Y Li, AJ Link… - Natural Product …, 2024 - pubs.rsc.org
Covering: 1992 up to 2023 Since their discovery, lasso peptides went from peculiarities to
be recognized as a major family of ribosomally synthesized and post-translationally modified …