Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …

Accurate diagnosis of traumatic brain injury (TBI) is critical to effective management and
intervention, but can be challenging in patients with mild TBI. A substantial number of …

Head computed tomography (CT) imaging is still a commonly obtained diagnostic test for
patients with minor head injury despite availability of clinical decision rules to guide imaging …

Traumatic brain injury (TBI) is a major health concern in the United States resulting in a
substantial number of hospitalizations and in a broad spectrum of symptoms and disabilities …

Traumatic brain injury (TBI) is a leading cause of mortality and long-term morbidity
worldwide. Despite decades of pre-clinical investigation, therapeutic strategies focused on …

Introduction Major organ-based in vitro diagnostic (IVD) tests like ALT/AST for the liver and
cardiac troponins for the heart are established, but an approved IVD blood test for the brain …

Background Blood biomarkers are valuable tools for elucidating complex cellular and
molecular mechanisms underlying traumatic brain injury (TBI). Profiling distinct classes of …

Currently colorimetric paper lateral flow strips (PLFS) encounter two major limitations, that is,
low sensitivity and severe interference from complex sample matrices such as blood. These …

Introduction Traumatic brain injury (TBI) is a major global health issue, resulting in
debilitating consequences to families, communities, and health-care systems. Prior research …

The purpose of this study was to correlate the early levels of glial fibrillary acidic protein
(GFAP) and neurofilament light protein (NF-L) with outcome in patients with mild traumatic …