Background Melanin plays an important role in protecting human skin, while excessive
synthesis of melanin can cause abnormal pigmentation and induce skin diseases. Long …

Skin pigmentation is a result of melanin produced by melanocytes in the epidermis.
Melanocyte activity, along with the type and distribution of melanins, is the main driver for …

Casein kinase-1 alpha (CK1α) is a multifunctional protein kinase that belongs to the
serine/threonine kinases of the CK1α family. It is involved in various signaling pathways …

The anti-melanogenic bioactivities of phytophenolic compounds have been well recognized.
Riceberry rice contains a rich source of phenolic compounds that act as melanin inhibitors …

Cinnamic acids are aromatic acids primarily found in plants and plant-derived food. Phenolic
cinnamic acids, with one or more hydroxyl groups in the aromatic ring, often contribute to the …

To contribute enzymatic browning inhibitors to the food industry and also extend knowledge
about the phytochemical profile of the anti-tyrosinase plant Lepechinia meyenii, its ethanol …

UV light causes excessive oxidative stress and abnormal melanin synthesis, which results in
skin hyperpigmentation disorders such as freckles, sunspots, and age spots. Much research …

Pigmentation disorders are attributed to excessive melanin which can be produced by
tyrosinase. Therefore, tyrosinase is supposed to be a vital target for the treatment of …

张敏, 黄京平, 赵文, 王鹏, 金玥, 胡菡, 薛晓峰, 张金振*(中国农业科学院蜜蜂研究所农业农村部蜂
产品质量监督检验测试中心(北京), 北京100193) 摘要: 该研究采用分光光度法测定了10 …

Abstract Rationale: SOX10 (SRY-related HMG-box 10) and MITF-M (microphthalmia-
associated transcription factor M) restrict the expression of melanogenic genes, such as TYR …