Disrupted homeostasis in sickle cells: expanding the comprehension of metabolism adaptation and related therapeutic strategies

VS Bernardo, FF Torres, ACA Zucão, NA Chaves… - Tissue and Cell, 2025 - Elsevier
Sickle cell disease (SCD) is a hereditary hemolytic anemia associated with the alteration of
the membrane composition of the sickle erythrocytes, the loss of glycolysis, dysregulation of …

Red blood cell partitioning and segregation through vascular bifurcations in a model of sickle cell disease

X Cheng, C Caruso, WA Lam, MD Graham - arXiv preprint arXiv …, 2024 - arxiv.org
The impact of cell segregation and margination in blood disorders on microcirculatory
hemodynamics within bifurcated vessels are physiologically significant, yet poorly …

Endothelial inflammation: how many bad apples?

MJ Simmonds - Blood, 2024 - ashpublications.org
In this issue of Blood, Caruso and colleagues 1 provide compelling evidence that when the
exceptional flexibility of erythrocytes is impaired, the resultant aberrant wall interactions …