Classical and atypical scrapie in sheep and goats. Review on the etiology, genetic factors, pathogenesis, diagnosis, and control measures of both diseases
Simple Summary Classical scrapie is a prionic, neurological, consumptive, and chronic
disease that affects naturally domestic small ruminants. It was initially described in the UK …
disease that affects naturally domestic small ruminants. It was initially described in the UK …
Design and characterization of a 52K SNP chip for goats
G Tosser-Klopp, P Bardou, O Bouchez, C Cabau… - PloS one, 2014 - journals.plos.org
The success of Genome Wide Association Studies in the discovery of sequence variation
linked to complex traits in humans has increased interest in high throughput SNP …
linked to complex traits in humans has increased interest in high throughput SNP …
Prion and prion-like diseases in animals
Transmissible spongiform encephalopaties (TSEs) are fatal neurodegenerative diseases
characterized by the aggregation and accumulation of the misfolded prion protein in the …
characterized by the aggregation and accumulation of the misfolded prion protein in the …
Healthy goats naturally devoid of prion protein
SL Benestad, L Austbø, MA Tranulis, A Espenes… - Veterinary …, 2012 - Springer
Prion diseases such as scrapie in small ruminants, bovine spongiform encephalopathy
(BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in man, are fatal neurodegenerative …
(BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in man, are fatal neurodegenerative …
Resistance to classical scrapie in experimentally challenged goats carrying mutation K222 of the prion protein gene
PL Acutis, F Martucci, A D'Angelo, S Peletto… - Veterinary …, 2012 - Springer
Susceptibility of sheep to scrapie, a transmissible spongiform encephalopathy of small
ruminants, is strongly influenced by polymorphisms of the prion protein gene (PRNP) …
ruminants, is strongly influenced by polymorphisms of the prion protein gene (PRNP) …
Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom
W Goldmann, K Ryan, P Stewart, D Parnham… - Veterinary …, 2011 - Springer
The application of genetic breeding programmes to eradicate transmissible spongiform
encephalopathies in goats is an important aim for reasons of animal welfare as well as …
encephalopathies in goats is an important aim for reasons of animal welfare as well as …
Potential scrapie-associated polymorphisms of the prion protein gene (PRNP) in Korean native black goats
SK Kim, YC Kim, SY Won, BH Jeong - Scientific Reports, 2019 - nature.com
Small ruminants, including sheep and goats are natural hosts of scrapie, and the
progression of scrapie pathogenesis is strongly influenced by polymorphisms in the prion …
progression of scrapie pathogenesis is strongly influenced by polymorphisms in the prion …
Role of the Goat K222-PrPC Polymorphic Variant in Prion Infection Resistance
The prion protein-encoding gene (prnp) strongly influences the susceptibility of small
ruminants to transmissible spongiform encephalopathies (TSEs). Hence, selective breeding …
ruminants to transmissible spongiform encephalopathies (TSEs). Hence, selective breeding …
PrP-associated resistance to scrapie in five highly infected goat herds
F Corbiere, C Perrin-Chauvineau… - Journal of General …, 2013 - microbiologyresearch.org
The PrP gene polymorphisms at codons 142 (I/M), 154 (R/H), 211 (R/Q), 222 (Q/K) and 240
(S/P) and their association with susceptibility to classical scrapie infection were investigated …
(S/P) and their association with susceptibility to classical scrapie infection were investigated …
Genetic resistance to transmissible spongiform encephalopathies (TSE) in goats
EFSA Panel on Biological Hazards (BIOHAZ)… - EFSA …, 2017 - Wiley Online Library
Breeding programmes to promote resistance to classical scrapie, similar to those for sheep
in existing transmissible spongiform encephalopathies (TSE) regulations, have not been …
in existing transmissible spongiform encephalopathies (TSE) regulations, have not been …