Brain insulin resistance at the crossroads of metabolic and cognitive disorders in humans

S Kullmann, M Heni, M Hallschmid… - Physiological …, 2016 - journals.physiology.org
Ever since the brain was identified as an insulin-sensitive organ, evidence has rapidly
accumulated that insulin action in the brain produces multiple behavioral and metabolic …

Processing of primary and secondary rewards: a quantitative meta-analysis and review of human functional neuroimaging studies

G Sescousse, X Caldú, B Segura, JC Dreher - … & Biobehavioral Reviews, 2013 - Elsevier
One fundamental question concerning brain reward mechanisms is to determine how
reward-related activity is influenced by the nature of rewards. Here, we review the …

[HTML][HTML] Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity

D Val-Laillet, E Aarts, B Weber, M Ferrari… - NeuroImage: Clinical, 2015 - Elsevier
Functional, molecular and genetic neuroimaging has highlighted the existence of brain
anomalies and neural vulnerability factors related to obesity and eating disorders such as …

Reward mechanisms in obesity: new insights and future directions

PJ Kenny - Neuron, 2011 - cell.com
Food is consumed in order to maintain energy balance at homeostatic levels. In addition,
palatable food is also consumed for its hedonic properties independent of energy status …

Homeostasis meets motivation in the battle to control food intake

CR Ferrario, G Labouèbe, S Liu, EH Nieh… - Journal of …, 2016 - Soc Neuroscience
Signals of energy homeostasis interact closely with neural circuits of motivation to control
food intake. An emerging hypothesis is that the transition to maladaptive feeding behavior …

Obesity and the brain: how convincing is the addiction model?

H Ziauddeen, IS Farooqi, PC Fletcher - Nature Reviews Neuroscience, 2012 - nature.com
An increasingly influential perspective conceptualizes both obesity and overeating as a food
addiction accompanied by corresponding brain changes. Because there are far-reaching …

Flavor is in the brain

DM Small - Physiology & behavior, 2012 - Elsevier
Flavor is perhaps the most multi-modal of all of our sensory experiences. Here flavor is
defined as a perception that includes gustatory, oral-somatosensory, and retronasal …

Genetics of eating behavior: established and emerging concepts

ER Grimm, NI Steinle - Nutrition reviews, 2011 - academic.oup.com
Understanding why we eat and the motivational factors driving food choices is important for
addressing the epidemics of obesity, diabetes, and cardiovascular disease. Eating behavior …

Neural responses to visual food cues according to weight status: a systematic review of functional magnetic resonance imaging studies

KM Pursey, P Stanwell, RJ Callister, K Brain… - Frontiers in …, 2014 - frontiersin.org
Emerging evidence from recent neuroimaging studies suggests that specific food-related
behaviors contribute to the development of obesity. The aim of this review was to report the …

Anorexia nervosa and obesity are associated with opposite brain reward response

GKW Frank, JR Reynolds, ME Shott, L Jappe… - …, 2012 - nature.com
Anorexia nervosa (AN) is a severe psychiatric disorder associated with food avoidance and
malnutrition. In this study, we wanted to test whether we would find brain reward alterations …