The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

Nanotechnology has the potential to circumvent several drawbacks of conventional
therapeutic formulations. In fact, significant strides have been made towards the application …

Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Liposomes, which possess the properties of nano-scale, biofilm similar structure, excellent
biocompatibility, become more and more useful in the drug development as the delivery …

Since its first isolation in 1934, hyaluronic acid (HA) has been studied across a variety of
research areas. This unbranched glycosaminoglycan consisting of repeating disaccharide …

An important motivation for the use of nanomaterials and nanoarchitectures in cancer
therapy emanates from the widespread emergence of drug resistance. Although doxorubicin …

Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …

In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …

Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …