Alcohol and the brain–gut axis: the involvement of microglia and enteric glia in the process of neuro-enteric inflammation

MAS Khan, SL Chang - Cells, 2023 - mdpi.com
Binge or chronic alcohol consumption causes neuroinflammation and leads to alcohol use
disorder (AUD). AUD not only affects the central nervous system (CNS) but also leads to …

Dysbiosis of the gut microbiota and its effect on α-synuclein and prion protein misfolding: consequences for neurodegeneration

NU Mahbub, MM Islam, ST Hong… - Frontiers in Cellular and …, 2024 - frontiersin.org
Abnormal behavior of α-synuclein and prion proteins is the hallmark of Parkinson's disease
(PD) and prion illnesses, respectively, being complex neurological disorders. A primary …

Healthy and unhealthy aging and the human microbiome

KY Simbirtseva, PW O'Toole - Annual Review of Medicine, 2024 - annualreviews.org
An altered gut microbiome is a feature of many multifactorial diseases, and microbiome
effects on host metabolism, immune function, and possibly neurological function are …

Microbial gene expression during hibernation in arctic ground squirrels: Greater differences across gut sections than in response to pre-hibernation dietary protein …

K Grond, CL Buck, KN Duddleston - Frontiers in Genetics, 2023 - frontiersin.org
Obligate seasonal hibernators fast for 5–9 months depending on species yet resist muscle
atrophy and emerge with little lean mass loss. The role of the gut microbiome in host …

Beneficial effect of GABA-producing Lactiplantibacillus strain LPB145 isolated from cheese starters evaluated in anxiety-and depression-like behaviours in rats

J Lozano, S Fabius, S Fernández-Ciganda… - Beneficial …, 2024 - brill.com
In a previous study, we reported the in vitro potential probiotic and gamma-aminobutyric acid
(GABA) production, of several strains from a collection of Lactiplantibacillus (Lpb) strains …

Neurotoxicity and intestinal microbiota dysbiosis induced by per-and polyfluoroalkyl substances in crucian carp (Carassius auratus)

Y Zhao, M Wang, W Chu - Journal of Hazardous Materials, 2024 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) have been called" forever chemicals" due to
their inherent chemical stability. Their potential toxic effects on aquatic animals and health …

The microbiota-gut-brain-immune interface in the pathogenesis of neuroinflammatory diseases: a narrative review of the emerging literature

A Warren, Y Nyavor, N Zarabian, A Mahoney… - Frontiers in …, 2024 - frontiersin.org
Importance Research is beginning to elucidate the sophisticated mechanisms underlying
the microbiota-gut-brain-immune interface, moving from primarily animal models to human …

Dangers of the chronic stress response in the context of the microbiota-gut-immune-brain axis and mental health: a narrative review

A Warren, Y Nyavor, A Beguelin, LA Frame - Frontiers in Immunology, 2024 - frontiersin.org
More than 20% of American adults live with a mental disorder, many of whom are treatment
resistant or continue to experience symptoms. Other approaches are needed to improve …

Gut microbiome is associated with personality traits of free-ranging Tibetan macaques (Macaca thibetana)

M Xia, Y Xia, Y Sun, J Wang, J Lu, X Wang… - Frontiers in …, 2024 - frontiersin.org
Recent studies have emphasized that there is a strong link between the gut microbiome and
the brain that affects social behavior and personality in animals. However, the interface …

The Role of the Intestinal Flora and Its Derivatives in Neurocognitive Disorders: A Narrative Review from Surgical Perspective

J Huang, TS Qin, Y Bo, YJ Li, RS Liu, Y Yu, XD Li… - Molecular …, 2024 - Springer
Perioperative neurocognitive dysfunction is a significant concern for population health,
impacting postoperative recovery and increasing the financial burden on patients. With an …