Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome
R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
Obstructive sleep apnea in cardiovascular disease: a review of the literature and proposed multidisciplinary clinical management strategy
JR Tietjens, D Claman, EJ Kezirian… - Journal of the …, 2019 - Am Heart Assoc
Cardiovascular disease (CVD) remains a highly prevalent cause of morbidity and mortality,
both in the United States and worldwide. In parallel with the development of new and …
both in the United States and worldwide. In parallel with the development of new and …
Obstructive sleep apnea: current perspectives
AM Osman, SG Carter, JC Carberry… - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences …
safety, and economic consequences. On an individual level, the causes and consequences …
Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy
DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
People develop obstructive sleep apnoea (OSA) for different reasons. The ability to
understand these reasons, easily identify them in individual patients, and develop therapies …
understand these reasons, easily identify them in individual patients, and develop therapies …
Adult obstructive sleep apnoea
AS Jordan, DG McSharry, A Malhotra - The Lancet, 2014 - thelancet.com
Obstructive sleep apnoea is an increasingly common disorder of repeated upper airway
collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include …
collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include …
Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets
Rationale: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among
patients but have not been well characterized. Objectives: To define carefully the proportion …
patients but have not been well characterized. Objectives: To define carefully the proportion …
Obstructive sleep apnea: transition from pathophysiology to an integrative disease model
WT McNicholas, D Pevernagie - Journal of sleep research, 2022 - Wiley Online Library
Obstructive sleep apnea (OSA) is characterised by recurring episodes of upper airway
obstruction during sleep and the fundamental abnormality reflects the inability of the upper …
obstruction during sleep and the fundamental abnormality reflects the inability of the upper …
Bi-directional relationships between co-morbid insomnia and sleep apnea (COMISA)
A Sweetman, L Lack, RD McEvoy, S Smith… - Sleep medicine …, 2021 - Elsevier
Insomnia and obstructive sleep apnea (OSA) commonly co-occur. Approximately 30–50% of
patients with OSA report clinically significant insomnia symptoms, and 30–40% of patients …
patients with OSA report clinically significant insomnia symptoms, and 30–40% of patients …
International consensus statement on obstructive sleep apnea
JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …
allows for consolidation and determination of the key factors important for clinical …
Phenotypes in obstructive sleep apnea: a definition, examples and evolution of approaches
AV Zinchuk, MJ Gentry, J Concato, HK Yaggi - Sleep medicine reviews, 2017 - Elsevier
Obstructive sleep apnea (OSA) is a complex and heterogeneous disorder and the apnea
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …