Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity

DA Bente, NL Forrester, DM Watts, AJ McAuley… - Antiviral research, 2013 - Elsevier
Crimean–Congo hemorrhagic fever (CCHF) is the most important tick-borne viral disease of
humans, causing sporadic cases or outbreaks of severe illness across a huge geographic …

Common features of enveloped viruses and implications for immunogen design for next-generation vaccines

FA Rey, SM Lok - Cell, 2018 - cell.com
Enveloped viruses enter cells by inducing fusion of viral and cellular membranes, a process
catalyzed by a specialized membrane-fusion protein expressed on their surface. This review …

Recent advances in the molecular and cellular biology of bunyaviruses

CT Walter, JN Barr - Journal of General Virology, 2011 - microbiologyresearch.org
The family Bunyaviridae of segmented, negative-stranded RNA viruses includes over 350
members that infect a bewildering variety of animals and plants. Many of these bunyaviruses …

Crimean-Congo hemorrhagic fever

S Shayan, M Bokaean, MR Shahrivar… - Laboratory …, 2015 - academic.oup.com
Crimean-Congo hemorrhagic fever virus (CCHFV) is a member of the Bunyaviridae family
and Nairovirus genus. The viral genome consists of 3 RNA segments of 12 kb (L), 6.8 kb (M) …

A novel vaccine against Crimean-Congo Haemorrhagic Fever protects 100% of animals against lethal challenge in a mouse model

KR Buttigieg, SD Dowall, S Findlay-Wilson… - PloS one, 2014 - journals.plos.org
Crimean-Congo Haemorrhagic Fever (CCHF) is a severe tick-borne disease, endemic in
many countries in Africa, the Middle East, Eastern Europe and Asia. Between 15–70% of …

Molecular insights into Crimean-Congo hemorrhagic fever virus

M Zivcec, FEM Scholte, CF Spiropoulou, JR Spengler… - Viruses, 2016 - mdpi.com
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen that causes high
morbidity and mortality. Efficacy of vaccines and antivirals to treat human CCHFV infections …

Recent advances in bunyavirus glycoprotein research: precursor processing, receptor binding and structure

RJG Hulswit, GC Paesen, TA Bowden, X Shi - Viruses, 2021 - mdpi.com
The Bunyavirales order accommodates related viruses (bunyaviruses) with segmented,
linear, single-stranded, negative-or ambi-sense RNA genomes. Their glycoproteins form …

A Look into Bunyavirales Genomes: Functions of Non-Structural (NS) Proteins

SS Leventhal, D Wilson, H Feldmann, DW Hawman - Viruses, 2021 - mdpi.com
In 2016, the Bunyavirales order was established by the International Committee on
Taxonomy of Viruses (ICTV) to incorporate the increasing number of related viruses across …

A DNA vaccine for Crimean-Congo hemorrhagic fever protects against disease and death in two lethal mouse models

AR Garrison, CJ Shoemaker, JW Golden… - PLoS neglected …, 2017 - journals.plos.org
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus capable of causing a
severe hemorrhagic fever disease in humans. There are currently no licensed vaccines to …

Crimean–Congo hemorrhagic fever virus: advances in vaccine development

T Tipih, FJ Burt - BioResearch Open Access, 2020 - liebertpub.com
Crimean–Congo hemorrhagic fever (CCHF) is a severe human disease with mortality rates
of up to 30%. The disease is widespread in Africa, Asia, the Middle East and Eastern …