The vascular blood–brain barrier is a highly regulated interface between the blood and
brain. Its primary function is to protect central neurons while signaling the presence of …

The pathobiology of traumatic and nontraumatic spinal cord injury (SCI), including
degenerative myelopathy, is influenced by neuroinflammation. The neuroinflammatory …

Simple Summary Glioblastoma multiforme (GBM) is the most aggressive tumor type in the
central nervous system. Hypoxia, defined as a lack of sufficient oxygen in tissues, is the most …

Abstract Background/Purpose: Rhodiola crenulata (Hook. f. et Thoms.) H. Ohba (R.
crenulate), a famous and characteristic Tibetan medicine, has been demonstrated to exert …

Endothelial cells throughout the body are heterogeneous, and this is tightly linked to the
specific functions of organs and tissues. Heterogeneity is already determined from …

The blood brain barrier (BBB) is a vital structure to protect the brain, tightly filtering the
passage of nutrients and molecules from the blood to the brain. This is critical for …

Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system
(CNS) and the most common non-traumatic cause of neurological disability in young adults …

Sleep-disordered breathing, ranging from habitual snoring to severe obstructive sleep
apnea, is a prevalent public health issue. Despite rising interest in sleep and awareness of …

Diseases of the central nervous system (CNS) are often associated with vascular
disturbances or inflammation and frequently both. Consequently, endothelial cells and …

Brain endothelial cells (BEC) of the vascular blood-brain barrier (BBB) interact with many
different cell types in the brain, including microglia, the brain's resident immune cells …