[HTML][HTML] Advancing clinical trials for inherited retinal diseases: recommendations from the Second Monaciano Symposium

DA Thompson, A Iannaccone, RR Ali… - … vision science & …, 2020 - arvojournals.org
Major advances in the study of inherited retinal diseases (IRDs) have placed efforts to
develop treatments for these blinding conditions at the forefront of the emerging field of …

Stargardt macular dystrophy and therapeutic approaches

K Fujinami, N Waheed, Y Laich, P Yang… - British Journal of …, 2024 - bjo.bmj.com
Stargardt macular dystrophy (Stargardt disease; STGD1; OMIM 248200) is the most
prevalent inherited macular dystrophy. STGD1 is an autosomal recessive disorder caused …

Progression of Stargardt disease as determined by fundus autofluorescence over a 12-month period: ProgStar report no. 11

RW Strauss, X Kong, A Ho, A Jha, S West… - JAMA …, 2019 - jamanetwork.com
Importance Sensitive outcome measures for disease progression are needed for treatment
trials of Stargardt disease. Objective To estimate the progression rate of atrophic lesions in …

[HTML][HTML] Prospective cohort study of childhood-onset Stargardt disease: fundus autofluorescence imaging, progression, comparison with adult-onset disease, and …

M Georgiou, T Kane, P Tanna, Z Bouzia… - American journal of …, 2020 - Elsevier
Purpose To determine the reliability and repeatability of quantitative evaluation of areas of
decreased autofluorescence (DAF) from fundus autofluorescence (FAF) images and track …

[HTML][HTML] Prognostication in stargardt disease using fundus autofluorescence: improving patient care

MD Varela, Y Laich, SA Hashem, OA Mahroo… - Ophthalmology, 2023 - Elsevier
Purpose To explore fundus autofluorescence (FAF) imaging as an alternative to
electroretinography as a noninvasive, quick, and readily interpretable method to predict …

Unmet needs in ophthalmology: a European Vision Institute-consensus roadmap 2019–2025

C Cursiefen, F Cordeiro, J Cunha-Vaz… - Ophthalmic …, 2019 - karger.com
Purpose: To define unmet needs in ophthalmology that can realistically be addressed in the
next 5 years (2019–2025) and describe potential avenues for research to address these …

Progression of Rare Inherited Retinal Dystrophies May Be Monitored by Adaptive Optics Imaging

K Samelska, JP Szaflik, B Śmigielska… - Life, 2023 - mdpi.com
Inherited retinal dystrophies (IRDs) are bilateral genetic conditions of the retina, leading to
irreversible vision loss. This study included 55 eyes afflicted with IRDs affecting the macula …

Quantitative fundus autofluorescence in ABCA4-related retinopathy-functional relevance and genotype-phenotype correlation

PL Müller, M Gliem, M McGuinnes, J Birtel… - American Journal of …, 2021 - Elsevier
Purpose To investigate lipofuscin-related quantitative autofluorescence measures and their
association with demographic characteristics, retinal structure, retinal function and genotype …

[HTML][HTML] A workshop on measuring the progression of atrophy secondary to Stargardt disease in the ProgStar studies: findings and lessons learned

AM Ervin, RW Strauss, MI Ahmed… - … Vision Science & …, 2019 - jov.arvojournals.org
Abstract The Progression of Atrophy Secondary to Stargardt Disease (ProgStar) studies
were designed to measure the progression of Stargardt disease through the use of fundus …

Correlations of full-field stimulus threshold with functional and anatomical outcome measurements in advanced retinitis pigmentosa

WK Ngo, LA Jenny, AH Kim, M Kolesnikova… - American journal of …, 2023 - Elsevier
Purpose To compare full-field stimulus (FST) threshold values to conventional functional and
anatomical measures commonly used in clinical practice. Design Cross-sectional study …