Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves
an important scaffolding role at focal adhesions by recruiting structural and signaling …

Protein-tyrosine phosphatases (PTPs) remove phosphate groups from tyrosine residues,
and thereby propagate or inhibit signal transduction, and hence influence cellular processes …

Small extracellular vesicles (sEVs) play a pivotal role in tumor progression by mediating
intercellular communication in the tumor microenvironment (TME). Syntenin-1 induces …

Reactive oxygen species (ROS), traditionally viewed as toxic by‐products that cause
damage to biomolecules, now are clearly recognized as key modulators in a variety of …

Epithelial-mesenchymal transition (EMT) is thought to contribute to metastasis and
chemoresistance in patients with hepatocellular carcinoma (HCC), leading to their poor …

Breast cancer is linked to hyperactivation of protein tyrosine kinases (PTKs), and recent
studies have unveiled that selective tyrosine dephosphorylation by protein tyrosine …

The protein tyrosine phosphatase (PTP) family is involved in multiple cellular functions and
plays an important role in various pathological and physiological processes. In many chronic …

Prostate cancer is a heterogeneous disease, and one of the main obstacles in its
management is the inability to foresee its course. Therefore, novel biomarkers are needed …

Protein phosphatases are primarily responsible for dephosphorylation modification within
signal transduction pathways. Phosphatase of regenerating liver-3 (PRL-3) is a dual-specific …

PTPN12 is a cytoplasmic protein tyrosine phosphatase (PTP) reported to be a tumor
suppressor in breast cancer, through its capacity to dephosphorylate oncogenic receptor …