The genetic basis of systemic lupus erythematosus: what are the risk factors and what have we learned

M Teruel, ME Alarcón-Riquelme - Journal of autoimmunity, 2016 - Elsevier
The genome-wide association study is a free-hypothesis approach based on screening of
thousands or even millions of genetic variants distributed throughout the whole human …

Genetic advances in systemic lupus erythematosus: an update

L Chen, DL Morris, TJ Vyse - Current opinion in rheumatology, 2017 - journals.lww.com
Genetic advances in systemic lupus erythematosus: an update : Current Opinion in
Rheumatology Genetic advances in systemic lupus erythematosus: an update : Current …

Relationship between genetic risk and age of diagnosis in systemic lupus erythematosus

D Dominguez, S Kamphuis, J Beyene, J Wither… - The Journal of …, 2021 - jrheum.org
Objective. Specific risk alleles for childhood-onset systemic lupus erythematosus SLE
(cSLE) vs adult-onset SLE (aSLE) patients have not been identified. The aims of this study …

Trying to understand the genetics of atopic dermatitis

S Stemmler, S Hoffjan - Molecular and cellular probes, 2016 - Elsevier
Atopic dermatitis (AD) is a common and complex skin disease associated with both genetic
and environmental factors. Loss-of-function mutations in the filaggrin gene, encoding a …

Autoimmune diseases in China

R Li, X Sun, X Liu, Y Yang, Z Li - Advances in immunology, 2019 - Elsevier
Autoimmune diseases, such as rheumatoid arthritis, systematic lupus erythematosus and
Sjögren's syndrome, are a group of diseases characterized by the activation of immune cells …

[HTML][HTML] Independent Replication on Genome-Wide Association Study Signals Identifies IRF3 as a Novel Locus for Systemic Lupus Erythematosus

F Zhang, YF Wang, Y Zhang, Z Lin, Y Cao… - Frontiers in …, 2020 - frontiersin.org
Systemic lupus erythematosus (SLE) is a genetically complex autoimmune disease. Despite
the significant progress made in identifying susceptibility genes for SLE, the genetic …

[HTML][HTML] Novel linkage disequilibrium clustering algorithm identifies new lupus genes on meta-analysis of GWAS datasets

M Saeed - Immunogenetics, 2017 - Springer
Systemic lupus erythematosus (SLE) is a complex disorder. Genetic association studies of
complex disorders suffer from the following three major issues: phenotypic heterogeneity …

Genetic studies on systemic lupus erythematosus in East Asia point to population differences in disease susceptibility

YF Wang, YL Lau, W Yang - … Journal of Medical Genetics Part C …, 2019 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease with extreme
clinical heterogeneity and significant differences between populations. East Asian …

The 330 risk loci known for systemic lupus erythematosus (SLE): a review

V Laurynenka, JB Harley - Frontiers in Lupus, 2024 - frontiersin.org
An in-depth literature review of up to 2023 reveals 330 risk loci found by genetic association
at p≤ 5× 10− 8, with systemic lupus erythematosus (SLE) in at least one study of 160 …

[HTML][HTML] The impact of vitamin D on cognitive dysfunction in mice with systemic lupus erythematosus

LJ Yan, P Wu, DM Gao, J Hu, Q Wang… - … Medical Journal of …, 2019 - ncbi.nlm.nih.gov
The Impact of Vitamin D on Cognitive Dysfunction in Mice with Systemic Lupus Erythematosus
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …