Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

The neuropeptide landscape of human prefrontal cortex

W Zhong, S Barde, N Mitsios, C Adori… - Proceedings of the …, 2022 - National Acad Sciences
Human prefrontal cortex (hPFC) is a complex brain region involved in cognitive and
emotional processes and several psychiatric disorders. Here, we present an overview of the …

Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques

MR Lee, TA Shnitko, SW Blue, AV Kaucher… - Nature …, 2020 - nature.com
Oxytocin may have promise as a treatment for neuropsychiatric disorders. Its therapeutic
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …

The role of dietary advanced glycation end products in metabolic dysfunction

D Sergi, H Boulestin, FM Campbell… - Molecular Nutrition & …, 2021 - Wiley Online Library
Advanced glycation end products (AGEs) are a heterogeneous group of molecules
produced, non‐enzymatically, from the interaction between reducing sugars and the free …

The transition to motherhood: linking hormones, brain and behaviour

C Servin-Barthet, M Martínez-García, C Pretus… - Nature Reviews …, 2023 - nature.com
We are witnessing a stark increase in scientific interest in the neurobiological processes
associated with pregnancy and maternity. Convergent evidence suggests that around the …

Challenges for measuring oxytocin: The blind men and the elephant?

EL MacLean, SR Wilson, WL Martin, JM Davis… - …, 2019 - Elsevier
Since its discovery more than a century ago, oxytocin has become one of the most
intensively studied molecules in behavioral biology. In the last five years …

[HTML][HTML] RAGE signaling regulates the progression of diabetic complications

K Taguchi, K Fukami - Frontiers in Pharmacology, 2023 - frontiersin.org
Diabetes, the ninth leading cause of death globally, is expected to affect 642 million people
by 2040. With the advancement of an aging society, the number of patients with diabetes …

Oxytocin and postpartum depression: A systematic review

TA Thul, EJ Corwin, NS Carlson, PA Brennan… - …, 2020 - Elsevier
Postpartum depression (PPD) is a significant mental health concern, especially for women in
vulnerable populations. Oxytocin (OT), a hormone essential for a variety of maternal tasks …

Sniffing oxytocin: Nose to brain or nose to blood?

S Yao, Y Chen, Q Zhuang, Y Zhang, C Lan, S Zhu… - Molecular …, 2023 - nature.com
In recent years ample studies have reported that intranasal administration of the
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …