Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

Abstract The Working Party makes more than 100 tabulated recommendations in
antimicrobial prescribing for the treatment of infections caused by multidrug-resistant (MDR) …

Abstract Background Ceftazidime-avibactam (CAZ-AVI) has been approved in Europe for
the treatment of complicated intra-abdominal and urinary tract infections, as well as hospital …

Urinary tract infections (UTIs) caused by Escherichia coli (E. coli) are the most common
types of infections in women. The antibiotic resistance of E. coli is increasing rapidly …

Scope These ESCMID guidelines address the targeted antibiotic treatment of third-
generation cephalosporin-resistant Enterobacterales (3GCephRE) and carbapenem …

Typical Klebsiella pneumoniae is an opportunistic pathogen, which mostly affects those with
weakened immune systems and tends to cause nosocomial infections. A subset of …

In this systematic review, we estimated the total number of episodes of bloodstream infection
(BSI) and deaths from BSI per year in North America and Europe, using data from population …

The rapid emergence and dissemination of antibiotic-resistant microorganisms in ICUs
worldwide threaten adequate antibiotic coverage of infected patients in this environment …

Epidemiology, risk factors, and clinical effect of infections by multiresistant bacteria in
cirrhosis are poorly known. This work was a prospective evaluation in two series of cirrhotic …

Extended-spectrum β-lactamases (ESBLs) are a group of plasmid-mediated, diverse,
complex and rapidly evolving enzymes that are posing a major therapeutic challenge today …