Breast cancer is a heterogeneous complex of diseases, a spectrum of many subtypes with
distinct biological features that lead to differences in response patterns to various treatment …

Breast cancer is a heterogeneous disease encompassing a variety of entities with distinct
morphological features and clinical behaviors. Although morphology is often associated with …

Germline mutations in BRCA1/2 predispose individuals to breast cancer (termed germline-
mutated BRCA1/2 breast cancer, gBRCA-BC) by impairing homologous recombination (HR) …

Purpose: To compare the clinical features, natural history, and outcomes for women with
“triple-negative” breast cancer with women with other types of breast cancer. Experimental …

ContextGene expression analysis has identified several breast cancer subtypes, including
basal-like, human epidermal growth factor receptor-2 positive/estrogen receptor negative …

Purpose: To investigate the incidence of germline and somatic BRCA1/2 mutations in
unselected patients with triple-negative breast cancer (TNBC) and determine the prognostic …

This review discusses the results of DNA microarray signatures in breast cancer. These
signatures have been useful in the classification of breast cancers, and they have an …

Triple-negative breast cancer (TNBC) is defined by a lack of expression of both estrogen
and progesterone receptor as well as human epidermal growth factor receptor 2. It is …

Of the estimated 1 million cases of breast cancer diagnosed annually worldwide, it is
estimated that over 170,000 will harbor the triple-negative (estrogen receptor/progesterone …

BACKGROUND. The purpose of the current study was to characterize the outcomes of
patients with metastatic triple‐negative breast cancers, including the risk and clinical …