[HTML][HTML] Advances and trends in omics technology development

X Dai, L Shen - Frontiers in Medicine, 2022 - frontiersin.org
The human history has witnessed the rapid development of technologies such as high-
throughput sequencing and mass spectrometry that led to the concept of 'omics' and …

[PDF][PDF] A simple guide to de novo transcriptome assembly and annotation

V Raghavan, L Kraft, F Mesny… - Briefings in …, 2022 - academic.oup.com
A transcriptome constructed from short-read RNA sequencing (RNA-seq) is an easily
attainable proxy catalog of protein-coding genes when genome assembly is unnecessary …

Lung adenocarcinoma and lung squamous cell carcinoma cancer classification, biomarker identification, and gene expression analysis using overlapping feature …

JW Chen, J Dhahbi - Scientific reports, 2021 - nature.com
Lung cancer is one of the deadliest cancers in the world. Two of the most common subtypes,
lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), have drastically …

Foodomics: Analytical opportunities and challenges

A Valdés, G Alvarez-Rivera… - Analytical …, 2021 - ACS Publications
Food analysis has traditionally been an important field of application of analytical chemistry.
Indeed, administrations, governments, consumers, and researchers worldwide rely on …

Transcriptomics technologies

R Lowe, N Shirley, M Bleackley, S Dolan… - PLoS computational …, 2017 - journals.plos.org
Transcriptomics technologies are the techniques used to study an organism's transcriptome,
the sum of all of its RNA transcripts. The information content of an organism is recorded in …

Cytoplasmic male sterility (CMS) in hybrid breeding in field crops

A Bohra, UC Jha, P Adhimoolam, D Bisht, NP Singh - Plant Cell Reports, 2016 - Springer
Key message A comprehensive understanding of CMS/Rf system enabled by modern omics
tools and technologies considerably improves our ability to harness hybrid technology for …

[HTML][HTML] Cellular interactions in the tumor microenvironment: the role of secretome

BR da Cunha, C Domingos, ACB Stefanini… - Journal of …, 2019 - ncbi.nlm.nih.gov
Over the past years, it has become evident that cancer initiation and progression depends
on several components of the tumor microenvironment, including inflammatory and immune …

[HTML][HTML] Tumor immune microenvironment and immunotherapy in non-small cell lung cancer: update and new challenges

S Xing, K Hu, Y Wang - Aging and disease, 2022 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is a serious threat to the health of older adults. Despite
the significant progress in immunotherapy, effective treatments for NSCLC remain limited …

Leveraging big data to transform target selection and drug discovery

B Chen, AJ Butte - Clinical Pharmacology & Therapeutics, 2016 - Wiley Online Library
The advances of genomics, sequencing, and high throughput technologies have led to the
creation of large volumes of diverse datasets for drug discovery. Analyzing these datasets to …

From immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning

LS Li, L Yang, L Zhuang, ZY Ye, WG Zhao… - Military Medical …, 2023 - Springer
Latent tuberculosis infection (LTBI) has become a major source of active tuberculosis (ATB).
Although the tuberculin skin test and interferon-gamma release assay can be used to …