Envelope stress responses: balancing damage repair and toxicity

AM Mitchell, TJ Silhavy - Nature Reviews Microbiology, 2019 - nature.com
The Gram-negative envelope is a complex structure that consists of the inner membrane, the
periplasm, peptidoglycan and the outer membrane, and protects the bacterial cell from the …

The complex Rcs regulatory cascade

E Wall, N Majdalani, S Gottesman - Annual review of …, 2018 - annualreviews.org
RcsB, a response regulator of the FixJ/NarL family, is at the center of a complex network of
regulatory inputs and outputs. Cell surface stress is sensed by an outer membrane …

Kaptive 2.0: updated capsule and lipopolysaccharide locus typing for the Klebsiella pneumoniae species complex

MMC Lam, RR Wick, LM Judd, KE Holt… - Microbial …, 2022 - microbiologyresearch.org
The outer polysaccharide capsule and lipopolysaccharide (LPS) antigens are key targets for
novel control strategies targeting Klebsiella pneumoniae and related taxa from the K …

High-throughput discovery of phage receptors using transposon insertion sequencing of bacteria

KE Kortright, BK Chan… - Proceedings of the …, 2020 - National Acad Sciences
As the most abundant microbes on Earth, novel bacteriophages (phages; bacteria-specific
viruses) are readily isolated from environmental samples. However, it remains challenging …

Pivotal roles of the outer membrane polysaccharide export and polysaccharide copolymerase protein families in export of extracellular polysaccharides in gram …

L Cuthbertson, IL Mainprize, JH Naismith… - Microbiology and …, 2009 - Am Soc Microbiol
Many bacteria export extracellular polysaccharides (EPS) and capsular polysaccharides
(CPS). These polymers exhibit remarkably diverse structures and play important roles in the …

Antimicrobial peptides in combination with citronellal efficiently kills multidrug resistance bacteria

Z Yang, S He, Y Wei, X Li, A Shan, J Wang - Phytomedicine, 2023 - Elsevier
Abstract Background Antimicrobial peptides (AMPs) are considered as the most potential
alternatives to antibiotics, but they have several drawbacks, including high cost, medium …

Large mutational target size for rapid emergence of bacterial persistence

HS Girgis, K Harris, S Tavazoie - Proceedings of the …, 2012 - National Acad Sciences
Phenotypic heterogeneity displayed by a clonal bacterial population permits a small fraction
of cells to survive prolonged exposure to antibiotics. Although first described over 60 y ago …

The Rcs phosphorelay: more than just a two-component pathway

DJ Clarke - Future microbiology, 2010 - Taylor & Francis
The Rcs phosphorelay is a complex signaling pathway found in many, but not all, members
of the Enterobacteriaceae. The complexity of this pathway is due to the direct involvement of …

Production and characterization of the intra‐and extracellular carbohydrates and polymeric substances (Eps) of three sea‐ice diatom species, and evidence for a …

SN Aslam, T Cresswell‐Maynard… - Journal of …, 2012 - Wiley Online Library
Diatoms and their associated extracellular polymeric substances (EPS) are major
constituents of the microalgal assemblages present within sea ice. Yields and chemical …

New insights into the non-orthodox two component Rcs phosphorelay system

XP Guo, YC Sun - Frontiers in Microbiology, 2017 - frontiersin.org
The Rcs phosphorelay system, a non-orthodox two-component regulatory system, integrates
environmental signals, regulates gene expression, and alters the physiological behavior of …