A meta-analysis-based adverse outcome pathway for the male reproductive toxicity induced by microplastics and nanoplastics in mammals

Y Hu, M Shen, C Wang, Q Huang, R Li, G Dorj… - Journal of hazardous …, 2024 - Elsevier
The male reproductive toxicity of microplastics (MPs) and nanoplastics (NPs) has attracted
great attention, but the latent mechanisms remain fragmented. This review performed the …

[HTML][HTML] Pinostrobin alleviates testicular and spermatological damage induced by polystyrene microplastics in adult albino rats

MU Ijaz, S Najam, A Hamza, R Azmat, A Ashraf… - Biomedicine & …, 2023 - Elsevier
Abstract Background Polystyrene microplastics (PS-MPs) have become major
environmental pollutants that adversely effects multiple organs specifically testicles …

Understanding the impact of nanoplastics on reproductive health: Exposure pathways, mechanisms, and implications

J Ye, Y Ren, Y Dong, D Fan - Toxicology, 2024 - Elsevier
Microplastic pollution is a pressing global environmental concern with particular urgency
surrounding the issue of nanoplastic particles. Plastic products exhibit a remarkable …

Hematological consequences of polyethylene microplastics toxicity in male rats: Oxidative stress, genetic, and epigenetic links

AA Farag, HS Youssef, RE Sliem, WB El Gazzar… - Toxicology, 2023 - Elsevier
Microplastics (MPs) pollution is a newly emerging environmental issue. MPs can accumulate
within animals and humans, which can pose a serious health threat. Petroleum-based …

Impact of polyethylene microplastics exposure on kallikrein-3 levels, steroidal-thyroidal hormones, and antioxidant status in murine model: protective potentials of …

SA Kehinde, TP Fatokun, AT Olajide, SM Praveena… - Scientific Reports, 2024 - nature.com
The widespread presence of microplastics in the environment has raised significant
concerns regarding their potential impact on human and animal health. Among various …

Evaluation of possible attenuative role of chrysoeriol against polyethylene microplastics instigated testicular damage: A biochemical, spermatogenic and histological …

MU Ijaz, F Saher, N Aslam, A Hamza, H Anwar… - Food and Chemical …, 2023 - Elsevier
The current study was designed to evaluate the protective role of chrysoeriol against
polyethylene microplastics (PE-MP) induced testicular damage. Forty eight male rats were …

Ameliorative effect of herbacetin against cyclophosphamide-induced nephrotoxicity in rats via attenuation of oxidative stress, inflammation, apoptosis and …

MU Ijaz, S Mustafa, R Batool, H Naz… - Human & …, 2022 - journals.sagepub.com
Herbacetin (HBN) is a glycosylated flavonoid, which possesses numerous pharmacological
properties. Cyclophosphamide (CYC) is a chemotherapeutic drug that adversely affects the …

Gum Acacia attenuates cisplatin toxic effect spermatogenesis dysfunction and infertility in rats

AE Nofal, YA Okdah, MI Rady, HZ Hassaan - International journal of …, 2023 - Elsevier
This study aimed to investigate the potential benefits Gum Arabic/Acacia senegal (GA) in
mitigating the harmful effects of cisplatin (CP) on spermatogenesis and testicular health in …

Isorhamnetin: a flavonoid, attenuated doxorubicin-induced testicular injury via regulation of steroidogenic enzymes and apoptotic signaling gene expression in male …

S Mustafa, MU Ijaz, Q ul Ain, T Afsar… - Toxicology …, 2022 - academic.oup.com
Background Male reproductive damage is one of the most adverse side effects of
doxorubicin (DOX). Isorhamnetin is a natural flavonoid, which displays remarkable …

[HTML][HTML] Juglanin cures polyethylene microplastics-induced testicular damage in rats

K Alvi, A Hamza, N Ehsan, M Batool, MZ Salar… - Journal of King Saud …, 2024 - Elsevier
The current research was planned to evaluate the ameliorative role of juglanin (Jug) against
polyethylene microplastics (PEMP) prompted testicular impairments. 48 rats were allocated …