Chromothripsis in cancer

M Simovic-Lorenz, A Ernst - Nature Reviews Cancer, 2024 - nature.com
Chromothripsis is a mutational phenomenon in which a single catastrophic event generates
extensive rearrangements of one or a few chromosomes. This extreme form of genome …

Modern biology of extrachromosomal DNA: A decade-long voyage of discovery

QL Yang, Y Xie, K Qiao, JYS Lim, S Wu - Cell Research, 2025 - nature.com
Genomic instability is a hallmark of cancer and is a major driving force of tumorigenesis. A
key manifestation of genomic instability is the formation of extrachromosomal DNAs …

Innovations in computational biology: RECOMB 2024 Special Issue

J Ma, B Berger - Genome Research, 2024 - genome.cshlp.org
The 28th International Conference on Research in Computational Molecular Biology
(RECOMB 2024) took place from April 29 to May 2, 2024, in Cambridge, Massachusetts …