Purpose For several years, oncological positron emission tomography (PET) has developed
beyond 2-deoxy-2-[18 F] fluoro-D-glucose ([18 F] FDG). This umbrella review of meta …

The advent of hybrid Positron Emission Tomography/Computed Tomography (PET/CT) and
PET/Magnetic Resonance Imaging (MRI) scanners resulted in an increased clinical …

Fibroblast activation protein (FAP) is a protein biomarker widely expressed in most solid
human malignancies of epithelial origin. In recent years, a number of FAP-targeted small …

Background: FAP radiopharmaceuticals show promise for cancer diagnosis; however, their
limited tumor residency hinders treatment. This study compared two FAPi derivatives, DOTA …

Breast cancer, with its global prevalence and impact on women's health, necessitates
effective early detection and accurate staging for optimal patient outcomes. Traditional …

Tumors consist of not only malignant cells but also stroma cells which include vascular and
inflammatory cells and activated fibroblasts and may contribute up to more than 90% of the …

Breast cancer is a common but heterogeneous disease characterized by several biologic
features, including tumor grade, hormone receptor status, human epidermal growth factor …

Purpose Radiopharmaceutical therapies targeting fibroblast activation protein (FAP) have
shown promising efficacy against many tumor types. But radiopharmaceuticals alone in most …

Fibroblast activation protein (FAP) has emerged as a highly promising target for cancer
diagnostic imaging and targeted radionuclide therapy. To exploit the therapeutic potential of …

Summary FES PET/CT demonstrates its usefulness in assessing ER expression and
predicting response to therapy in luminal breast cancer, with implications for treatment …