[HTML][HTML] Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?

RS O'Neill, A Stoita - World journal of gastroenterology, 2021 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is a leading cause of cancer related mortality on a global scale. The
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …

The role of miRNA-128 in the development and progression of gastrointestinal and urogenital cancer

GRL Al-Awsi, SA Jasim, Y Fakri Mustafa… - Future …, 2022 - Taylor & Francis
Increasing data have shown the significance of various miRNAs in malignancy. In this
regard, parallel to its biological role in normal tissues, miRNA-128 (miR-128) has been …

MicroRNA-301a promotes pancreatic cancer invasion and metastasis through the JAK/STAT3 signaling pathway by targeting SOCS5

H Hu, Q Zhang, W Chen, T Wu, S Liu, X Li… - …, 2020 - academic.oup.com
Pancreatic cancer is one of the most lethal digestive malignant tumors. We had previously
found that microRNA-301a (miR-301a) is a oncogenic microRNA whose recognized …

HOXD8 hypermethylation as a fully sensitive and specific biomarker for biliary tract cancer detectable in tissue and bile samples

E Loi, C Zavattari, A Tommasi, L Moi, M Canale… - British Journal of …, 2022 - nature.com
Background Biliary tract cancers (BTC) are rare but highly aggressive tumours with poor
prognosis, usually detected at advanced stages. Herein, we aimed at identifying BTC …

MicroRNA‑744‑5p is downregulated in colorectal cancer and targets SEPT2 to suppress the malignant phenotype

W Zhang, K Liao, D Liu - Molecular medicine reports, 2021 - spandidos-publications.com
Abstract MicroRNA (miR)‑744‑5p serves a pivotal role in the progression of multiple cancers;
however, the function of miR‑744‑5p in colorectal cancer (CRC) remains largely unknown. In …

Diagnostic utility of quantitative analysis of microRNA in bile samples obtained during endoscopic retrograde cholangiopancreatography for malignant biliary strictures

N Kuniyoshi, H Imazu, R Masuzaki, M Yamazaki… - PLoS …, 2023 - journals.plos.org
Background The sensitivity of bile cytology for malignant biliary strictures is not adequate. To
overcome this limitation, we evaluated whether quantitative analysis of microRNAs …

OmicSelector: automatic feature selection and deep learning modeling for omic experiments

K Stawiski, M Kaszkowiak, D Mikulski, P Hogendorf… - BioRxiv, 2022 - biorxiv.org
ABSTRACT A crucial phase of modern biomarker discovery studies is selecting the most
promising features from high-throughput screening assays. Here, we present the …

Novel miRNA biomarkers for patients with Duchenne muscular dystrophy

Q Meng, J Zhang, J Zhong, D Zeng, D Lan - Frontiers in Neurology, 2022 - frontiersin.org
Creatine kinase (CK) as a biomarker has long been expected to be replaced by other fluid
biomarkers for Duchenne muscular dystrophy (DMD) because it is independent of disease …

miR‐744‐5p inhibits cellular proliferation and invasion via targeting ARF1 in epithelial ovarian cancer

LG Zhao, J Wang, J Li, QF Li - The Kaohsiung Journal of …, 2020 - Wiley Online Library
Abstract miR‐744‐5p has been demonstrated to play an important role in cancer
progression. However, the functions of miR‐744‐5p in epithelial ovarian cancer (EOC) are …

Functional mechanism of hsa-miR-128-3p in epithelial-mesenchymal transition of pancreatic cancer cells via ZEB1 regulation

T Zheng, W Han, A Wang, Y Wang - PeerJ, 2022 - peerj.com
Pancreatic cancer (PC) often correlates with high mortality due to late diagnosis, rapid
metastasis, and resistance to chemotherapy. miR-128-3p has been validated as a tumor …