Role and Interrelationship Between Myeloid-Derived Suppressor Cells and CD4+ T Cells in Different Types of Infections: A Review

S Basak, A Ghosh, A Biswas, D Bhattacharya… - Proceedings of the …, 2024 - Springer
Abstract Myeloid-Derived Suppressor Cells (MDSCs), also known as 'Natural Suppressor
Cells (NSCs)','Immature Myeloid Cells,(IMCs), or 'Myeloid Suppressor Cells'(MSCs), are …

Polymorphonuclear myeloid-derived suppressor cells regulates immune recovery during HIV infection through PD-L1 and TGF-β pathways

Z Wang, Y Hu, J Song, P Ma, H Xia - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
Background Although MDSCs are widely recognized for their immunoinhibitory effects in
pathological conditions, their function during HIV infection particularly within the …

Bivalent SMAC mimetic APG-1387 reduces HIV reservoirs and limits viral rebound in humanized mice

J Jain, TNQ Pham, S Begum, MC Romero-Medina… - iScience, 2024 - cell.com
Latent viral reservoirs (VRs) represent a main barrier to HIV cure. Thus, developing new
approaches that can purge and eliminate VRs paves the path toward achieving an HIV-1 …

[HTML][HTML] Persistent T cell proliferation and MDSCs expansion precede incomplete CD4+ T cell recovery in people with acute HIV-1 infection with early ART

Z Li, P Yan, R Wang, X Lu, Y Zhang, B Su, X Zhang… - Heliyon, 2023 - cell.com
HIV-1 infection causes T cell dysfunction that cannot be fully restored by anti-retroviral
therapy (ART). Myeloid-derived suppressor cells (MDSCs) expand and suppress T cell …

Protective and pathological roles of regulatory immune cells in human cytomegalovirus infection following hematopoietic stem cell transplantation

H Namdari, M Hosseini, M Yazdanifar… - Reviews in Medical …, 2022 - Wiley Online Library
Human cytomegalovirus (HCMV) is ubiquitously prevalent. Immune system in healthy
individuals is capable of controlling HCMV infection; however, HCMV can be life …