Dengue virus life cycle: viral and host factors modulating infectivity

IA Rodenhuis-Zybert, J Wilschut, JM Smit - Cellular and molecular life …, 2010 - Springer
Abstract Dengue virus (DENV 1-4) represents a major emerging arthropod-borne pathogen.
All four DENV serotypes are prevalent in the (sub) tropical regions of the world and infect 50 …

Dengue virus control of type I IFN responses: a history of manipulation and control

JA Castillo Ramirez… - Journal of Interferon & …, 2015 - liebertpub.com
The arthropod-borne diseases caused by dengue virus (DENV) are a major and emerging
problem of public health worldwide. Infection with DENV causes a series of clinical …

Alpha-mangostin inhibits viral replication and suppresses nuclear factor kappa B (NF-κB)-mediated inflammation in dengue virus infection

M Tarasuk, P Songprakhon, T Chieochansin… - Scientific Reports, 2022 - nature.com
Severe dengue virus (DENV) infection results from viral replication and dysregulated host
immune response, which trigger massive cytokine production/cytokine storm. The result is …

How antibodies alter the cell entry pathway of dengue virus particles in macrophages

NV Ayala-Nunez, TE Hoornweg, DPI van de Pol… - Scientific reports, 2016 - nature.com
Antibody-dependent enhancement of dengue virus (DENV) infection plays an important role
in the exacerbation of DENV-induced disease. To understand how antibodies influence the …

Alpha-mangostin inhibits both dengue virus production and cytokine/chemokine expression

M Tarasuk, P Songprakhon, P Chimma, P Sratongno… - Virus research, 2017 - Elsevier
Since severe dengue virus (DENV) infection in humans associates with both high viral load
and massive cytokine production–referred to as “cytokine storm”, an ideal drug for treatment …

[HTML][HTML] Infection and activation of human peripheral blood monocytes by dengue viruses through the mechanism of antibody-dependent enhancement

P Sun, K Bauza, S Pal, Z Liang, S Wu, C Beckett… - Virology, 2011 - Elsevier
Human monocytes are susceptible to dengue virus (DV) infection through an FcR-
dependent pathway known as antibody-dependent enhancement (ADE). In this study …

Immature dengue virus is infectious in human immature dendritic cells via interaction with the receptor molecule DC-SIGN

MKS Richter, JM da Silva Voorham, S Torres Pedraza… - PloS one, 2014 - journals.plos.org
Background Dengue Virus (DENV) is the most common mosquito-borne viral infection
worldwide. Important target cells during DENV infection are macrophages, monocytes, and …

Impairment of CD4+ T Cell Polarization by Dengue Virus–Infected Dendritic Cells

AJ Chase, FA Medina… - Journal of Infectious …, 2011 - academic.oup.com
Background. The production of type I interferon alpha/beta (IFN-α/β) is crucial to viral
clearance during dengue virus (DENV) infection; however, in vitro–infected dendritic cells …

Serum levels of IFN‐β are associated with days of evolution but not with severity of dengue

RE Pech Torres, RM Cedillo Rivera… - Journal of Medical …, 2016 - Wiley Online Library
The serum levels of beta interferon (IFN‐β) were evaluated in clinical samples taken in the
acute phase of dengue fever for 107 patients during the 2011 dengue outbreak in Yucatán …

Evaluación de los perfiles de respuesta a interferón inducidos como respuesta a la infección con el virus del dengue

D Arellanos Soto - 2015 - eprints.uanl.mx
Introducción: El dengue es la principal enfermedad viral transmitida a humanos por
artrópodos. Una de las características del cuadro clínico de la infección por el virus del …