Three of the most fundamental questions in biology are how individual cells differentiate to
form tissues, how tissues function in a coordinated and flexible fashion and which gene …

Biological processes are often dynamic, thus researchers must monitor their activity at
multiple time points. The most abundant source of information regarding such dynamic …

The recent advent of methods for high-throughput single-cell molecular profiling has
catalyzed a growing sense in the scientific community that the time is ripe to complete the …

An internal time-keeping mechanism has been observed in almost every organism studied
from archaea to humans. This circadian clock provides a competitive advantage in fitness …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …

Productive cell proliferation involves efficient and accurate splitting of the dividing cell into
two separate entities. This orderly process reflects coordination of diverse cytological events …

Characterization of the transcriptional regulatory network of the normal cell cycle is essential
for understanding the perturbations that lead to cancer. However, the complete set of cycling …

Background It is widely accepted that orthologous genes between species are conserved at
the sequence level and perform similar functions in different organisms. However, the level …

Nearly 20% of the budding yeast genome is transcribed periodically during the cell division
cycle. The precise temporal execution of this large transcriptional program is controlled by a …

To evaluate the taste characteristics of Chinese rice wine, wine samples sourced from
different vintage years were analyzed using liquid chromatographic analysis, sensory …