The AMP-activated protein kinase (AMPK) is a central regulator of multiple metabolic
pathways and may have therapeutic importance for treating obesity, insulin resistance, type …

Altered immune cell phenotype and chronic inflammation are key features shared by various
chronic diseases. Evidence from nutritional interventions aimed at alleviating inflammation …

Perivascular adipose tissue (PVAT) is an additional special type of adipose tissue
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …

A number of factors contribute to the complex process of aging, which finally define whether
someone will or not develop age-associated chronic diseases in late life. These …

Brown (BAT) and white (WAT) adipose tissues play distinct roles in maintaining whole-body
energy homeostasis, and their dysfunction can contribute to non-alcoholic fatty liver disease …

Abstract Purpose of Review The global prevalence of type 2 diabetes (T2D) is escalating at
alarming rates, demanding the development of additional classes of therapeutics to further …

Objective Fibroblast-growth factor 21 (FGF21) is thought to be important in metabolic
regulation. Recently, low protein diets have been shown to increase circulating FGF21 …

Prolonged intervention studies investigating molecular metabolism are necessary for a
deeper understanding of dietary effects on health. Here we provide mechanistic information …

Abstract Background and aims The Nordic diet (ND), is supposed to be associated with a
reduced cardiovascular risk; however, clinical trials have led to inconsistent results …

Low-grade inflammation (LGI) has been suggested to be involved in the development of
chronic diseases. Healthy dietary patterns, such as the Mediterranean diet (MD), may …