Function of serine/arginine-rich splicing factors in hematopoiesis and hematopoietic malignancies
H Zhang, H Zhu, H Peng, Y Sheng - Cancer Cell International, 2024 - Springer
The serine/arginine-rich splicing factors (SRSFs) play an important role in regulating the
alternative splicing of precursor RNA (pre-RNA). During this procedure, introns are removed …
alternative splicing of precursor RNA (pre-RNA). During this procedure, introns are removed …
Distinct cuproptosis patterns in hepatocellular carcinoma patients correlate with unique immune microenvironment characteristics and cell-cell communication …
Y Wang, X Mang, X Guo, J Pu - Frontiers in Immunology, 2024 - frontiersin.org
Background Hepatocellular carcinoma (HCC), a prevalent cancer, is linked to cuproptosis in
tumor progression. However, cuproptosis's impact on HCC prognosis and its role in the …
tumor progression. However, cuproptosis's impact on HCC prognosis and its role in the …
CSF3R mutated myeloid neoplasms: beyond chronic neutrophilic leukemia
CSF3R activating mutation is a genetic hallmark of chronic neutrophilic leukemia (CNL), and
is also present in a subset of atypical chronic myeloid leukemia (aCML), but infrequent in …
is also present in a subset of atypical chronic myeloid leukemia (aCML), but infrequent in …
[PDF][PDF] Comprehensive Analyses of the Effects of the Small-Molecule Inhibitor of the UHM Domain in the Splicing Factor Gene U2AF1 in Leukemia Cells
X Yuan, MK Sabzvar, AD Patil, K Chinnaswamy… - assets-eu.researchsquare.com
11. Thermal Shift Assay S14 12. Cell lines and culture conditions S14 13. RNA-seq
experiment S15 14. Western blots S16 15. Crystal structure determination S16 16. Cell …
experiment S15 14. Western blots S16 15. Crystal structure determination S16 16. Cell …
[PDF][PDF] Targeted isoform-specific analysis of Csf3r alternative splicing in splicing factor mutant myeloid cells
CH Ambrose, AL Rich, SS Zinkel - wp0.vanderbilt.edu
SRSF2P95H/WT (henceforth P95H) mutations are commonly found in certain types of blood
diseases [1],[2] and are linked to intricate changes in how mRNA is spliced throughout the …
diseases [1],[2] and are linked to intricate changes in how mRNA is spliced throughout the …