Comparison of preribosomal RNA processing pathways in yeast, plant and human cells–focus on coordinated action of endo‐and exoribonucleases

R Tomecki, PJ Sikorski, M Zakrzewska‐Placzek - FEBS letters, 2017 - Wiley Online Library
Proper regulation of ribosome biosynthesis is mandatory for cellular adaptation, growth and
proliferation. Ribosome biogenesis is the most energetically demanding cellular process …

Roles of RNase P and its subunits

N Jarrous - Trends in Genetics, 2017 - cell.com
Recent studies show that nuclear RNase P is linked to chromatin structure and function.
Thus, variants of this ribonucleoprotein (RNP) complex bind to chromatin of small noncoding …

Coevolution of RNA and protein subunits in RNase P and RNase MRP, two RNA processing enzymes

B Zhou, F Wan, KX Lei, P Lan, J Wu, M Lei - Journal of Biological Chemistry, 2024 - ASBMB
RNase P and RNase mitochondrial RNA processing (MRP) are ribonucleoproteins (RNPs)
that consist of a catalytic RNA and a varying number of protein cofactors. RNase P is …

The many faces of RNA-based RNase P, an RNA-world relic

HD Phan, LB Lai, WJ Zahurancik, V Gopalan - Trends in biochemical …, 2021 - cell.com
RNase P is an essential enzyme that catalyzes removal of the 5′ leader from precursor
transfer RNAs. The ribonucleoprotein (RNP) form of RNase P is present in all domains of life …

lncRNA RMRP knockdown suppress hepatocellular carcinoma biological activities via regulation miRNA‐206/TACR1

Z Hongfeng, J Andong, S Liwen… - Journal of cellular …, 2020 - Wiley Online Library
Long noncoding RNA, RNA component of mitochondrial RNA processing endoribonuclease
(RMRP) plays an important role in cancer development and is closely correlated with …

Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP

A Perederina, D Li, H Lee, C Bator, I Berezin… - Nature …, 2020 - nature.com
RNase MRP is an essential eukaryotic ribonucleoprotein complex involved in the maturation
of rRNA and the regulation of the cell cycle. RNase MRP is related to the ribozyme-based …

Footprinting analysis of interactions between the largest eukaryotic RNase P/MRP protein Pop1 and RNase P/MRP RNA components

RD Fagerlund, A Perederina, I Berezin, AS Krasilnikov - RNA, 2015 - rnajournal.cshlp.org
Ribonuclease (RNase) P and RNase MRP are closely related catalytic ribonucleoproteins
involved in the metabolism of a wide range of RNA molecules, including tRNA, rRNA, and …

Multifaceted investigation of ribonuclease MRP in Cyanidioschyzon merolae: Heat stress response, canonical rRNA processing pathway, structural prediction and …

S Fumador - 2024 - unbc.arcabc.ca
RNase MRP is a ribonucleoprotein complex essential for ribosome biogenesis in eukaryotes
including Saccharomyces cerevisiae and humans. Mutations in the single genomic locus …

Moonlighting phosphatase activity of Klenow DNA polymerase in the presence of RNA

Q Zhao, W Yang, T Qin, Z Huang - Biochemistry, 2018 - ACS Publications
RNA is a key player in the cellular central dogma, including RNA transcription and protein
synthesis. However, it is unknown whether RNA can directly interfere with DNA synthesis …

Novel insights into the regulation of nucleolar function and longevity by ncl-1

T Popkes-van Oepen - 2022 - kups.ub.uni-koeln.de
The nucleolus is primarily described as the control center for ribonuclear protein assembly
and rRNA synthesis. However, there is increasing evidence that the nucleolus also plays a …