Diabetes mellitus and its metabolic complications: the role of adipose tissues

L Dilworth, A Facey, F Omoruyi - International journal of molecular …, 2021 - mdpi.com
Many approaches have been used in the effective management of type 2 diabetes mellitus.
A recent paradigm shift has focused on the role of adipose tissues in the development and …

Physical exercise-induced myokines and muscle-adipose tissue crosstalk: a review of current knowledge and the implications for health and metabolic diseases

LG Leal, MA Lopes, ML Batista Jr - Frontiers in physiology, 2018 - frontiersin.org
Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic
regimen of regular exercise and pharmaceutical treatment is often recommended for their …

Central obesity and increased risk of dementia more than three decades later

RA Whitmer, DR Gustafson, E Barrett-Connor… - Neurology, 2008 - AAN Enterprises
Background: Numerous reports show that a centralized distribution of adiposity is a more
dangerous risk factor for cardiovascular disease and diabetes than total body obesity. No …

[图书][B] Obesity epidemiology

F Hu - 2008 - books.google.com
During the past twenty years there has been a dramatic increase in obesity in the United
States. An estimated thirty percent of adults in the US are obese; in 1980, only fifteen percent …

Nonalcoholic steatohepatitis

EM Brunt - Seminars in liver disease, 2004 - thieme-connect.com
BACKGROUND The diagnosis of NAFLD and NASH remains one of clinicopathologic
correlation.[1][2][3] In evaluation of subjects suspected to have NAFLD or NASH, standard …

[HTML][HTML] Sarcopenia, obesity, and inflammation—results from the trial of angiotensin converting enzyme inhibition and novel cardiovascular risk factors study

M Cesari, SB Kritchevsky, RN Baumgartner… - The American journal of …, 2005 - Elsevier
Background: Age-related body-composition changes are associated with health-related
outcomes in elders. This relation may be explained by inflammation and hemostatic …

[HTML][HTML] The clinical biochemistry of obesity

KA Sikaris - The Clinical Biochemist Reviews, 2004 - ncbi.nlm.nih.gov
Obesity is essentially an excessive accumulation of triacylglycerols in fatty tissue that is the
net result of excessive energy intake compared to energy usage. Severe forms of the …

Metabolically healthy obesity—heterogeneity in definitions and unconventional factors

I Brandão, MJ Martins, R Monteiro - Metabolites, 2020 - mdpi.com
The concept of heterogeneity among obese individuals in their risk for developing metabolic
dysfunction and associated complications has been recognized for decades. At the origin of …

Relationship between maternal central obesity and the risk of gestational diabetes mellitus: a systematic review and meta‐analysis of cohort studies

D Yao, Q Chang, QJ Wu, SY Gao… - Journal of diabetes …, 2020 - Wiley Online Library
Objective. Nowadays, body mass index (BMI) is used to evaluate the risk stratification of
obesity‐related pregnancy complications in clinics. However, BMI cannot reflect fat …

Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats

R Meli, M Pacilio, GM Raso, E Esposito… - …, 2004 - academic.oup.com
Obesity, from declining estrogen levels after menopause, increases the risk of heart disease,
diabetes, and hypertension. Ovariectomy (OVX) in rats is a good model of estrogen …